SEC Filing | Biogen

View:

2008 ANNUAL MEETING OF STOCKHOLDERS OF BIOGEN IDEC INC. ------------------- PROXY STATEMENT OF CARL C. ICAHN ALEXANDER J. DENNER ANNE B. YOUNG RICHARD C. MULLIGAN VINCENT J. INTRIERI KEITH A. MEISTER DAVID S. SCHECHTER ICAHN PARTNERS LP ICAHN PARTNERS MASTER FUND LP ICAHN PARTNERS MASTER FUND II LP ICAHN PARTNERS MASTER FUND III LP HIGH RIVER LIMITED PARTNERSHIP BARBERRY CORP. HOPPER INVESTMENTS LLC ICAHN OFFSHORE LP ICAHN ONSHORE LP ICAHN CAPITAL LP IPH GP LLC ICAHN ENTERPRISES HOLDINGS L.P. ICAHN ENTERPRISES G.P. INC. BECKTON CORP. ------------------- To Our Fellow Biogen Stockholders: This Proxy Statement and the accompanying GOLD proxy card are being furnished to stockholders ("Stockholders") of Biogen Idec Inc. ("Biogen") in connection with the solicitation of proxies by Carl C. Icahn and certain of his affiliates and associates, to be used at the 2008 Annual Meeting (the "Annual Meeting") of Stockholders of Biogen which is scheduled to be held at 9:00 A.M., local time, on June 19, 2008, at the American Academy of Arts and Sciences, 136 Irving Street, Cambridge, MA 02138, and at any adjournments, postponements or continuations thereof. This Proxy Statement and the GOLD proxy card are first being furnished to Stockholders on or about May 16, 2008. At the Annual Meeting, the Participants (as hereinafter defined) will seek to elect to the Board of Directors of Biogen - Dr. Alexander J. Denner, Dr. Anne B. Young and Professor Richard C. Mulligan (each a "Nominee", and collectively, the "Nominees") who has each consented to being named in this Proxy Statement and, if elected, to serve as a director. In addition, Biogen's Amended and Restated ByLaws (the "Bylaws") provide for a three-class classified board, the size of which may be expanded by a vote of the Board. In order to provide the Stockholders with the ability to elect a majority of Stockholder nominated directors following the 2009 annual meeting, the Participants will seek to amend the ByLaws to fix the number of directors at twelve. For example, if the Stockholders elect Dr. Alexander J. Denner, Dr. Anne B. Young and Professor Richard C. Mulligan to the Board at the 2008 Annual Meeting, and in 2009, a Stockholder nominates, and the Stockholders elect, four director nominees at the 2009 annual meeting, then the Board would include seven Stockholder nominated directors. If the Bylaw Amendments (as defined below) are adopted by the Stockholders at the 2008 Annual Meeting and the Board is fixed at 12 directors, then those seven Stockholder nominated directors elected over the course of two annual meetings would constitute a majority of the Board. However, because the current Bylaws allow the Board to expand the size of the Board, if the Bylaw Amendments are not adopted at the 2008 Annual Meeting and the Board decides to expand the size of the Board (despite the possibility that such a decision to expand the size of the Board could constitute a breach of fiduciary duty under applicable law), then those seven Stockholder nominated directors would merely constitute a minority of the Board. As such, the Participants will seek to amend the Bylaws (collectively, the "Bylaw Amendments"): o to replace the first sentence of Section 3.1 of the Bylaws, which reads: "The number of directors that shall constitute the entire Board initially shall be twelve (12); provided, however, that the number of directors that shall constitute the entire Board shall be fixed from time to time by resolution adopted by a majority of the entire Board", in its entirety with the following sentence: "The number of directors that shall constitute the entire Board shall be twelve (12)." o to delete, in its entirety, the first sentence of Section 3.2 of the Bylaws which reads: "The number of members of the Board may be increased at any time as provided in Section 3.1 above." o to delete, in their entirety, the words "and newly created directorships resulting from any increase in the authorized number of directors", appearing in the second sentence of Section 3.2 of the Bylaws which reads, in its entirety: "Sole power to fill vacancies and newly created directorships resulting from any increase in the authorized number of directors shall be vested in the Board, and each director so chosen shall hold office until the next annual election at which the term of the class to which they have been elected expires and until such director's successor is duly elected and qualified or until such director's earlier resignation, removal from office, death or incapacity." DR. ALEXANDER J. DENNER, DR. ANNE B. YOUNG AND PROFESSOR RICHARD C. MULLIGAN URGE STOCKHOLDERS TO VOTE FOR EACH OF THEM AS DIRECTORS AND TO VOTE FOR EACH OF THE BYLAW AMENDMENTS. The Nominees and each of the other Participants have no interest in Biogen other than through the beneficial ownership (if any) of shares of Common Stock, par value $.0005 per share, of Biogen (the "Shares") or other securities (if any) of Biogen as disclosed herein, and, in the case of Dr. Young and Professor Mulligan, pursuant to an agreement in which certain affiliates of Carl C. Icahn have agreed to pay each of Dr. Young and Professor Mulligan $25,000 and to indemnify each such Nominee with respect to certain costs incurred by each such Nominee in connection with the proxy contest relating to the Annual Meeting (the "Nominee Agreement"). DR. ALEXANDER J. DENNER, DR. ANNE B. YOUNG AND PROFESSOR RICHARD C. MULLIGAN ARE COMMITTED TO ACTING IN THE BEST INTEREST OF ALL STOCKHOLDERS OF BIOGEN. WE URGE YOU TO VOTE YOUR GOLD PROXY CARD FOR DR. ALEXANDER J. DENNER, DR. ANNE B. YOUNG AND PROFESSOR RICHARD C. MULLIGAN AND FOR EACH OF THE BYLAW AMENDMENTS. IMPORTANT According to Biogen's Proxy Statement, the Bylaws and applicable law, the election of the Nominees requires the affirmative vote of a plurality of the votes cast by the holders of Biogen's Common Stock at a meeting at which a quorum is present in person or represented by proxy. The amendment of the Bylaws requires the affirmative vote of a majority of the Shares issued and outstanding and entitled to vote. As a result, your vote is extremely important. We urge you to mark, sign, date, and return the enclosed GOLD proxy card to vote FOR the election of each Nominee and FOR the Bylaw Amendments. WE URGE YOU NOT TO SIGN ANY PROXY CARD SENT TO YOU BY BIOGEN. IF YOU HAVE ALREADY DONE SO, YOU MAY REVOKE YOUR PROXY BY DELIVERING A LATER-DATED GOLD PROXY CARD IN THE ENCLOSED POSTAGE-PREPAID ENVELOPE, EXECUTING A VOTE VIA INTERNET OR TELEPHONE, OR BY VOTING IN PERSON AT THE ANNUAL MEETING. SEE "VOTING PROCEDURES" AND "PROXY PROCEDURES" BELOW. If you have any questions or require any assistance in executing your proxy, please call: Georgeson Inc. Stockholders call toll-free: (800) 377-9583 Banks and Brokers call collect: (212) 440-9800 Only holders of record of Biogen's voting securities as of the close of business on April 21, 2008 (the "Record Date") are entitled to notice of, and to attend and to vote at, the Annual Meeting and any adjournments or postponements thereof. According to the proxy statement of Biogen filed with the Securities and Exchange Commission ("Biogen's Proxy Statement"), as of the Record Date, there were outstanding 291,522,405 shares of Common Stock. Stockholders of record at the close of business on the Record Date will be entitled to one vote at the Annual Meeting for each share of Common Stock of Biogen held on the Record Date. As of the Record Date, the Participants and their affiliates beneficially owned an aggregate of 12,435,904 shares of Common Stock, representing approximately 4.26 % of the outstanding shares of Common Stock. The Participants and their affiliates intend to vote such shares FOR the election of the Nominees and FOR the Bylaw Amendments. VOTE FOR THE NOMINEES AND FOR THE BYLAW AMENDMENTS BY USING THE ENCLOSED GOLD PROXY TO VOTE TODAY - BY TELEPHONE, BY INTERNET, OR BY MARKING, SIGNING, DATING AND RETURNING THE GOLD PROXY CARD IN THE POSTAGE-PAID ENVELOPE PROVIDED TO YOU.

PARTICIPANTS IN SOLICITATION OF PROXIES In addition to the Nominees (who are Dr. Alexander J. Denner, Dr. Anne B. Young and Professor Richard C. Mulligan), the participants in the solicitation of proxies (the "Participants") from stockholders of Biogen Idec Inc. ("Biogen" or the "Corporation") include the following: Mr. Carl C. Icahn, Icahn Partners LP, a Delaware limited partnership ("Icahn Partners"), Icahn Partners Master Fund LP, a Cayman Islands limited partnership ("Icahn Master"), Icahn Partners Master Fund II LP, a Cayman Islands limited partnership ("Icahn Master II"), Icahn Partners Master Fund III LP, a Cayman Islands limited partnership ("Icahn Master III"), High River Limited Partnership, a Delaware limited partnership ("High River"), Barberry Corp., a Delaware corporation ("Barberry"), Hopper Investments LLC, a Delaware limited liability company ("Hopper"), Beckton Corp., a Delaware corporation ("Beckton"), Icahn Enterprises G.P. Inc., a Delaware corporation ("Icahn Enterprises GP"), Icahn Enterprises Holdings L.P., a Delaware limited partnership ("Icahn Enterprises Holdings"), IPH GP LLC, a Delaware limited liability company ("IPH"), Icahn Capital LP, a Delaware limited partnership ("Icahn Capital"), Icahn Onshore LP, a Delaware limited partnership ("Icahn Onshore"), Icahn Offshore LP, a Delaware limited partnership ("Icahn Offshore"), Mr. Vincent J. Intrieri, Mr. Keith A. Meister and Mr. David S. Schechter. The address of Icahn Partners, High River, Barberry, Hopper, Icahn Enterprises GP, Icahn Enterprises Holdings, Beckton, IPH, Icahn Capital, Icahn Onshore and Icahn Offshore is White Plains Plaza, 445 Hamilton Avenue - Suite 1210, White Plains, NY 10601. The address of Icahn Master, Icahn Master II and Icahn Master III is c/o Walkers SPV Limited, P.O. Box 908GT, 87 Mary Street, George Town, Grand Cayman, Cayman Islands. Mr. Icahn's, Dr. Denner's, Mr. Intrieri's, Mr. Meister's and Mr. Schechter's business address is c/o Icahn Associates Corp., 767 Fifth Avenue, 47th Floor, New York, NY 10153. Dr. Young's business address is Neurology Service, 720 Wang Building, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114. Professor Mulligan's business address is Harvard Gene Therapy Initiative, Harvard Institutes of Medicine, Suite 407, 4 Blackfan Circle, Boston, MA 02115. Icahn Partners, Icahn Master, Icahn Master II, Icahn Master III and High River (collectively, the "Icahn Parties") are entities controlled by Mr. Icahn. Messrs. Denner, Meister, Intrieri and Schechter are employees and/or officers and directors of the Icahn Parties and various other entities controlled by Mr. Icahn who may also participate in soliciting proxies from Biogen Stockholders. Messrs. Denner, Intrieri, Meister and Schechter do not own beneficially any interest in securities of Biogen, and will not receive any special compensation in connection with such solicitation. In connection with their employment by Mr. Icahn and his affiliated companies, Messrs. Denner, Meister, Intrieri and Schechter, among other employees, each has a participatory interest in the profits and fees derived by Mr. Icahn and/or his affiliated entities from Icahn Partners, Icahn Master, Icahn Master II and Icahn Master III (collectively, the "Funds"). Because only a portion of such profit interests are distributed and because of their other investments in the Funds, each of Messrs. Denner, Meister and Intrieri also has capital accounts in the Funds. Generally, in the aggregate: (i) Mr. Meister's profit interests and capital accounts in the Funds entitle him to less than 2% of the profits generated by the Funds; (ii) Mr. Intrieri's profit interests and capital accounts in the Funds entitle him to less than 2% of the profits generated by the Funds; (iii) Mr. Schechter's profit interests in the Funds entitle him to less than 1% of the profits generated by the Funds; and (iv) Dr. Denner's profit interests and capital accounts in the Funds entitle him to less than 2% of the profits generated by the Funds. Each of Icahn Partners, Icahn Master, Icahn Master II, Icahn Master III and High River is principally engaged in the business of investing in securities. Annex A attached hereto sets forth, as to the Nominees and the other Participants, all transactions in securities of Biogen effected during the past two years and their beneficial ownership of securities of Biogen. With respect to each Participant (including the Nominees), except as set forth herein or in any of the Annexes attached hereto, (i) such Participant is not, nor was within the past year, a party to any contract, arrangement or understanding with any person with respect to any securities of Biogen, including, but not limited to, joint ventures, loan or option arrangements, puts or calls, guarantees against loss or guarantees of profit, division of losses or profits, or the giving or withholding of proxies; and (ii) neither such Participant nor any of such Participant's associates have any arrangement or understanding with any person with respect to (A) any future employment by Biogen or its affiliates or (B) any future transactions to which Biogen or any of its affiliates will or may be a party. PROPOSAL 1 -- ELECTION OF DIRECTORS On January 24, 2008 the Icahn Parties delivered a letter to Biogen, notifying Biogen that the Icahn Parties nominate and will seek to elect at the Annual Meeting - Dr. Alexander J. Denner, Dr. Anne B. Young and Professor Richard C. Mulligan as members of the board of directors of Biogen. The Nominees, if elected, would serve a three-year term and hold office until the 2011 annual meeting of Stockholders and until a successor has been duly elected and qualified. Background information about each of the Nominees is set forth below. According to Biogen's Proxy Statement, the Board of Directors of Biogen (the "Board") intend to nominate four candidates for election as directors at the Annual Meeting. This proxy statement is soliciting proxies to elect not only Dr. Denner, Dr. Young and Professor Mulligan, but also the Biogen nominee other than Mr. Cecil B. Pickett, Ms. Lynn Schenk and Mr. Stelios Papadopoulos. This gives stockholders who wish to vote for Dr. Denner, Dr. Young and Professor Mulligan and such other person the ability to do so. Under applicable proxy rules we are required either to solicit proxies only for Dr. Denner, Dr. Young and Professor Mulligan, which could result in limiting the ability of Stockholders to fully exercise their voting rights with respect to Biogen's nominees, or to solicit for Dr. Denner, Dr. Young and Professor Mulligan and for fewer than all of Biogen's nominees, which enables a Stockholder who desires to vote for Dr. Denner, Dr. Young and Professor Mulligan to also vote for the Biogen nominee for whom we are soliciting proxies. Mr. Icahn notes that, subject to the Stockholders approval of the Bylaw Amendments, if Dr. Denner, Dr. Young and Professor Mulligan are elected, and if a majority of the Board members thereafter determines that it would be desirable that Mr. Cecil B. Pickett, Ms. Lynn Schenk and Mr. Stelios Papadopoulos serve as Board members, the Board could permit that result by increasing the size of the Board and adding Mr. Cecil B. Pickett, Ms. Lynn Schenk and Mr. Stelios Papadopoulos as additional members. Dr. Anne B. Young and Professor Richard C. Mulligan are each party to an agreement substantially in the form attached hereto as Annex B, pursuant to which the Icahn Parties have agreed to pay certain fees to each such Nominee and to indemnify each such Nominee with respect to certain costs incurred by each such Nominee in connection with the proxy contest relating to the Annual Meeting (the "Nominee Agreement"). Except as disclosed in this Proxy Statement, including the Annexes attached hereto and as provided in the Nominee Agreement (which, among other things, provides for a payment to each of Dr. Young and Professor Mulligan of $25,000), none of the Nominees receive any compensation from any of the Participants or any of their affiliates in connection with this proxy solicitation. Dr. Young and Professor Mulligan have an interest in the election of directors at the Annual Meeting pursuant to the Nominee Agreement relating to such Nominee. Dr. Denner has an interest in the election of directors at the Annual Meeting indirectly through his capital accounts and other investments in the Funds. The Nominees would not be barred from being considered independent under the independence requirements of The NASDAQ Stock Market, Inc. and the independence standards applicable to Biogen under paragraph (a)(1) of Item 407 of Regulation S-K under the Securities Exchange Act of 1934, as amended. Other than as disclosed in this Proxy Statement, including the Annexes attached hereto, (i) the Nominees are not, nor were they within the past year, a party to any contract, arrangement or understanding with any person with respect to any securities of Biogen, including, but not limited to, joint ventures, loan or option arrangements, puts or calls, guarantees against loss or guarantees of profit, division of losses or profits, or the giving or withholding of proxies; and (ii) none of the Nominees nor any of their respective associates have any arrangement or understanding with any person with respect to (A) any future employment by Biogen or its affiliates or (B) any future transactions to which Biogen or any of its affiliates will or may be a party. DR. ALEXANDER J. DENNER Dr. Alexander J. Denner, 38, serves as a Managing Director of entities affiliated with Carl C. Icahn, including Icahn Partners, Icahn Master, Icahn Master II and Icahn Master III. Dr. Denner has served in this position since August 2006. Icahn Partners, Icahn Master, Icahn Master II and Icahn Master III are private investment funds. From April 2005 to May 2006, Dr. Denner served as a portfolio manager specializing in healthcare investments for Viking Global Investors. Previously he served in a variety of roles at Morgan Stanley, beginning in 1996, including as portfolio manager of healthcare and biotechnology mutual funds. Since September 2006, Dr. Denner has served as a director of ImClone Systems Incorporated, a publicly traded biopharmaceutical company and has served as the chairman of the executive committee of ImClone. In addition, Dr. Denner has served as a director of Adventrx Pharmaceuticals Inc., a publicly traded biopharmaceutical company since October 2006. Dr. Denner currently serves as a director of HyperMed, Inc., a privately held company specializing in imaging platforms for medical and surgical applications. Dr. Denner received his S.B. degree from the Massachusetts Institute of Technology and his M.S., M.Phil. and Ph.D. degrees from Yale University. DR. ANNE B. YOUNG Dr. Young, 60, Julieanne Dorn Professor of Neurology at Harvard Medical School and the Chief, Neurology Service at Massachusetts General Hospital, is a researcher and clinician whose work has concentrated on neurotransmitter systems in the basal ganglia and their role in Huntington's, Alzheimer's and Parkinson's diseases. Dr. Young holds membership in both the Institute of Medicine and the American Academy of Arts and Sciences. Dr. Young was inducted as a Fellow in the Royal Academy of Physicians in London in 2005. Dr. Young is a Phi Beta Kappa, summa cum laude graduate of Vassar College who completed her medical studies at Johns Hopkins in 1973. She received a Ph.D. in Pharmacology from Johns Hopkins in 1974, and then completed residency training in neurology at the University of California, San Francisco. After residency, she joined the neurology faculty at the University of Michigan where she advanced to Professor in 1985. In 1991, she was recruited to the Massachusetts General Hospital as Chief of the Neurology Service and Julieanne Dorn Professor of Neurology at Harvard Medical School. Dr. Young provided some of the first evidence that glutamic acid is a neurotransmitter. Subsequently, she and her colleagues identified glutamate as a transmitter of corticostriatal and corticospinal tracts. Her laboratory first described techniques to measure subtypes of glutamate receptors autoradiographically and went on to demonstrate receptor alterations in Huntington's and Alzheimer's disease. Dr. Young's current research work includes elucidating cellular and systems mechanisms underlying the pathophysiology of neurodegenerative diseases such as Huntington's disease, Alzheimer's disease and Parkinson's disease. In an effort to help develop therapeutic targets for human disorders of movement, she is conducting studies on the vulnerability of neurons to excitotoxic injury and the selective expression of glutamate receptors in these neurons. Recently, she has discovered that transgenic animals expressing exon 1 of the huntingtin protein (Huntington's disease is caused by a mutation of the gene encoding this protein) have markedly altered receptors that may play a central role in the neuronal degeneration of Huntington's disease. Her studies suggest that mutant huntingtin may alter receptor expression selectively when it accumulates in the nucleus. Altered receptor expression occurs early and may contribute to selective cell death. Dr. Young serves on the editorial board of numerous biomedical journals and she has been the recipient of many awards and honors for her work. She is a member of the Scientific Advisory Boards of several voluntary organizations. She is the past President of the American Neurological Association and the Society for Neuroscience. PROFESSOR RICHARD C. MULLIGAN Professor Mulligan, 53, is the Mallinckrodt Professor of Genetics at Harvard Medical School, and Director of the Harvard Gene Therapy Initiative. Professor Mulligan received his B.S. degree from the Massachusetts Institute of Technology, and his Ph.D. from the Department of Biochemistry at Stanford University School of Medicine. After receiving postdoctoral training at the Center for Cancer Research at MIT, Professor Mulligan joined the MIT faculty and subsequently was appointed Professor of Molecular Biology and Member of the Whitehead Institute for Biomedical Research before moving to Children's Hospital and Harvard in 1996. His honors include the MacArthur Foundation Prize, the Rhodes Memorial Award of the American Association for Cancer Research, the ASMB-Amgen Award, and the Nagai Foundation International Prize. Professor Mulligan has been associated with a number of biotechnology companies, including Somatix Therapy Corporation (as founder and member of the Scientific Advisory Board and Board of Directors, and Chief Scientific Officer), Cell Genesys (as member of the Scientific Advisory Board) and ImClone, where he served on the Scientific Advisory Board and has been a Director and member of the Executive Committee since September 2006. He has also served on the National Institutes of Health's Recombinant DNA Advisory Committee and on the U.S. Food and Drug Administration Biological Response Modifiers Advisory Committee. WE STRONGLY URGE YOU TO VOTE FOR THE ELECTION OF DR. ALEXANDER J. DENNER, DR. ANNE B. YOUNG AND PROFESSOR RICHARD C. MULLIGAN BY MARKING, SIGNING, DATING AND RETURNING THE ENCLOSED GOLD PROXY CARD IN THE POSTAGE PAID ENVELOPE PROVIDED TO YOU WITH THIS PROXY STATEMENT OR BY USING THE GOLD PROXY CARD TO VOTE BY TELEPHONE OR INTERNET. IF YOU HAVE SIGNED THE GOLD PROXY CARD AND NO MARKING IS MADE, YOU WILL BE DEEMED TO HAVE GIVEN A DIRECTION TO VOTE ALL THE SHARES REPRESENTED BY THE GOLD PROXY CARD FOR THE ELECTION OF DR. ALEXANDER J. DENNER, DR. ANNE B. YOUNG, PROFESSOR RICHARD C. MULLIGAN AND THE BIOGEN NOMINEE OTHER THAN MR. CECIL B. PICKETT, MS. LYNN SCHENK AND MR. STELIO PAPADOPOULOS. PROPOSAL 2 -- BYLAW AMENDMENTS Biogen's ByLaws provide for a three-class classified board, the size of which may be expanded by a vote of the Board. In order to provide the Stockholders with the ability to elect a majority of Stockholder nominated directors following the 2009 annual meeting, the Participants will seek to amend the ByLaws to fix the number of directors at twelve. For example, if the Stockholders elect Dr. Alexander J. Denner, Dr. Anne B. Young and Professor Richard C. Mulligan to the Board at the 2008 Annual Meeting, and in 2009, a Stockholder nominates, and the Stockholders elect, four director nominees at the 2009 annual meeting, then the Board would include seven Stockholder nominated directors. If the Bylaw Amendments are adopted by the Stockholders at the 2008 Annual Meeting and the Board is fixed at 12 directors, then those seven Stockholder nominated directors elected over the course of two annual meetings would constitute a majority of the Board. However, because the current Bylaws allow the Board to expand the size of the Board, if the Bylaw Amendments are not adopted at the 2008 Annual Meeting and the Board decides to expand the size of the Board (despite the possibility that such a decision to expand the size of the Board could constitute a breach of fiduciary duty under applicable law), then those seven Stockholder nominated directors would merely constitute a minority of the Board. As such, the Participants will seek to amend the Bylaws: o to replace the first sentence of Section 3.1 of the Bylaws, which reads: "The number of directors that shall constitute the entire Board initially shall be twelve (12); provided, however, that the number of directors that shall constitute the entire Board shall be fixed from time to time by resolution adopted by a majority of the entire Board", in its entirety with the following sentence: "The number of directors that shall constitute the entire Board shall be twelve (12)." o to delete, in its entirety, the first sentence of Section 3.2 of the Bylaws which reads: "The number of members of the Board may be increased at any time as provided in Section 3.1 above." o to delete, in their entirety, the words "and newly created directorships resulting from any increase in the authorized number of directors", appearing in the second sentence of Section 3.2 of the Bylaws which reads, in its entirety: "Sole power to fill vacancies and newly created directorships resulting from any increase in the authorized number of directors shall be vested in the Board, and each director so chosen shall hold office until the next annual election at which the term of the class to which they have been elected expires and until such director's successor is duly elected and qualified or until such director's earlier resignation, removal from office, death or incapacity." WE STRONGLY URGE YOU TO VOTE FOR THE BYLAW AMENDMENTS BY MARKING, SIGNING, DATING AND RETURNING THE ENCLOSED GOLD PROXY CARD IN THE POSTAGE PAID ENVELOPE PROVIDED TO YOU WITH THIS PROXY STATEMENT OR BY USING THE GOLD PROXY CARD TO VOTE BY TELEPHONE OR INTERNET. IF YOU HAVE SIGNED THE GOLD PROXY CARD AND NO MARKING IS MADE, YOU WILL BE DEEMED TO HAVE GIVEN A DIRECTION TO VOTE ALL THE SHARES REPRESENTED BY THE GOLD PROXY CARD FOR THE BYLAW AMENDMENTS. OTHER MATTERS TO BE CONSIDERED AT THE ANNUAL MEETING According to Biogen's Proxy Statement, Biogen is soliciting proxies with respect to three proposals other than the election of directors and the Bylaw Amendments. Please refer to Biogen's Proxy Statement for a detailed discussion of these proposals, including various arguments in favor of and against such proposals. These proposals are outlined below. IF YOU HAVE SIGNED THE GOLD PROXY CARD AND NO MARKING IS MADE, YOU WILL BE DEEMED TO HAVE GIVEN A DIRECTION TO VOTE ALL OF THE SHARES REPRESENTED BY YOUR GOLD PROXY CARD (I) FOR PROPOSAL 3 BELOW, AND (II) AGAINST PROPOSALS 4 AND 5 BELOW. PROPOSAL 3 -- RATIFICATION OF SELECTION OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM At the Annual Meeting, the Stockholders will be asked to vote to ratify the selection of PricewaterhouseCoopers LLP as Biogen's independent registered public accounting firm. Biogen's Board of Directors recommended a vote for this proposal. The Participants intend to vote, and recommend that you vote, for this proposal. PROPOSAL 4 -- APPROVAL OF BIOGEN'S 2008 OMNIBUS EQUITY PLAN At the Annual Meeting, the Stockholders will be asked to vote to approve Biogen's 2008 Omnibus Equity Plan that will provide stock-based compensation to Biogen's employees. Biogen's Board of Directors recommended a vote for this proposal. The Participants intend to vote, and recommend that you vote, against this proposal. PROPOSAL 5 -- APPROVAL OF BIOGEN'S 2008 PERFORMANCE-BASED MANAGEMENT INCENTIVE PLAN At the Annual Meeting, the Stockholders will be asked to vote to approve Biogen's 2008 Performance-Based Management Incentive Plan that will provide a cash incentive program for certain members of management. Biogen's Board of Directors recommended a vote for this proposal. The Participants intend to vote, and recommend that you vote, against this proposal. OTHER PROPOSALS The Participants and their affiliates know of no other business to be presented at the Annual Meeting. If any other matters should properly come before the Annual Meeting, it is intended that the persons named on the enclosed GOLD proxy card will vote that proxy on such other matters in accordance with their judgment. VOTING PROCEDURES According to Biogen's Proxy Statement, the Bylaws and applicable law, holders of shares of Biogen's Common Stock, at the close of business on the Record Date are entitled to notice of, and to vote at, the Annual Meeting. Each share of Common Stock outstanding on the Record Date is entitled to one vote on each matter presented at the Annual Meeting. According to Biogen's Proxy Statement, the Bylaws and applicable law, directors are elected by a plurality of the votes cast by the holders of Biogen's Common Stock at a meeting at which a quorum is present. Plurality means that the individuals who receive the largest number of votes cast are elected as directors up to the maximum number of directors to be chosen at the meeting. Consequently, any shares not voted (whether by abstention, broker nonvote or otherwise) have no impact in the election of directors. A quorum is a majority of the Shares issued and outstanding and entitled to vote, present in person or represented by proxy at the Annual Meeting. The Shares represented by a proxy marked "withhold" or "abstain" will be considered present at the Annual Meeting for purposes of determining a quorum. According to Biogen's Proxy Statement, the Bylaws and applicable law, amendments to the Bylaws are effected by the affirmative vote of a majority of the Shares issued and outstanding and entitled to vote thereon. An affirmative vote means that a vote must be cast in favor of the Bylaw Amendments. Consequently, any shares not voted (whether by abstention, broker nonvoter or otherwise) would have the effect of a vote AGAINST the Bylaw Amendments. As of the Record Date, there were 291,522,405 Shares issued and outstanding. As a result, in order to amend the Bylaws, at least 145,761,203 Shares must be affirmatively voted in FAVOR of the Bylaw Amendments. According to Biogen's Proxy Statement, the Bylaws and applicable law, the affirmative vote of a majority of Shares present in person or represented by proxy at the Annual Meeting and entitled to vote thereon are required to (i) ratify the selection of the independent registered accounting firm, (ii) approve Biogen's 2008 Omnibus Equity Plan and (iii) approve Biogen's 2008 Performance-Based Management Incentive Plan. As explained in the detailed instructions on your GOLD proxy card, there are four ways you may vote. You may: 1. Sign, date and return the enclosed GOLD proxy card in the enclosed postage-paid envelope. We recommend that you vote on the GOLD proxy card even if you plan to attend the Annual Meeting; 2. Vote via the Internet by following the voting instructions on the GOLD proxy card or the voting instructions provided by your broker, bank or other holder of record. If you submit your vote by Internet, you may incur costs associated with electronic access, such as usage charges from Internet access providers and telephone companies; 3. Vote by telephone by following the voting instructions on the GOLD proxy card or the instructions provided by your broker, bank or other holder of record; or 4. Vote in person by attending the Annual Meeting. Written ballots will be distributed to Stockholders who wish to vote in person at the Annual Meeting. If you hold your Shares through a bank, broker or other custodian, you must obtain a legal proxy from such custodian in order to vote in person at the meeting. To submit a proxy with voting instructions by telephone please call the telephone number listed on the GOLD proxy card. Proxies may also be submitted over the Internet. Please refer to the GOLD proxy card for the website information. In each case Stockholders will be required to provide the unique control number which has been printed on each Stockholder's GOLD proxy card. In addition to the instructions that appear on the GOLD proxy card, step-by-step instructions will be provided by a recorded telephone message for those Stockholders submitting proxies by telephone, or at the designated website for those Stockholders submitting proxies over the Internet. Stockholders submitting their proxies with voting instructions by telephone or over the Internet will receive confirmation on the telephone that their vote by telephone was successfully submitted, and may provide an email address for confirmation that their vote by Internet was successfully submitted. Whether or not you are able to attend the Annual Meeting, you are urged to complete the enclosed GOLD proxy and return it in the enclosed self-addressed, prepaid envelope. All valid proxies received prior to the meeting will be voted. If you specify a choice with respect to any item by marking the appropriate box on the proxy, the Shares will be voted in accordance with that specification. IF NO SPECIFICATION IS MADE, THE SHARES WILL BE VOTED (I) FOR DR. ALEXANDER J. DENNER FOR DIRECTOR; (II) FOR DR. ANNE B. YOUNG FOR DIRECTOR; (III) FOR PROFESSOR RICHARD C. MULLIGAN FOR DIRECTOR; (IV) FOR THE PERSON WHO HAS BEEN NOMINATED BY BIOGEN TO SERVE AS DIRECTOR, OTHER THAN MR. CECIL B. PICKETT, MS. LYNN SCHENK AND MR. STELIOS PAPADOPOULOS; (V) FOR THE BYLAW AMENDMENTS; (VI) FOR THE RATIFICATION OF SELECTION OF THE INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM; (VII) AGAINST BIOGEN'S 2008 OMNIBUS EQUITY PLAN; (VIII) AGAINST BIOGEN'S 2008 PERFORMANCE-BASED MANAGEMENT INCENTIVE PLAN; AND (IX) IN THE PROXY HOLDERS' DISCRETION AS TO OTHER MATTERS THAT MAY PROPERLY COME BEFORE THE ANNUAL MEETING. If you have any questions or require any assistance in executing your proxy, please call: Georgeson Inc. Stockholders call toll-free: (800) 377-9583 Banks and Brokers call collect: (212) 440-9800 PROXY PROCEDURES IN ORDER FOR YOUR VIEWS TO BE REPRESENTED AT THE ANNUAL MEETING, PLEASE MARK, SIGN, DATE AND RETURN THE ENCLOSED GOLD PROXY CARD IN THE ENCLOSED POSTAGE-PREPAID ENVELOPE OR USE THE GOLD PROXY CARD TO VOTE BY TELEPHONE OR INTERNET. The accompanying GOLD proxy card will be voted at the Annual Meeting in accordance with your instructions on such card. Only holders of record as of the close of business on the Record Date will be entitled to vote. If you were a Stockholder of record on the Record Date, you will retain your voting rights at the Annual Meeting even if you sell such shares after the Record Date. Accordingly, it is important that you vote the shares held by you on the Record Date, or grant a proxy to vote such shares on the GOLD proxy card, even if you sell such shares after the Record Date. IF YOUR SHARES ARE HELD IN THE NAME OF A BROKERAGE FIRM, BANK, BANK NOMINEE OR OTHER INSTITUTION ON THE RECORD DATE, ONLY IT CAN VOTE SUCH SHARES AND ONLY UPON RECEIPT OF YOUR SPECIFIC INSTRUCTIONS. ACCORDINGLY, PLEASE CONTACT THE PERSON RESPONSIBLE FOR YOUR ACCOUNT AND INSTRUCT THAT PERSON TO EXECUTE ON YOUR BEHALF THE GOLD PROXY CARD AS SOON AS POSSIBLE. REVOCATION OF PROXIES Any Stockholders of record may revoke or change his or her proxy instructions at any time prior to the vote at the Annual Meeting by: o submitting a properly executed, subsequently dated GOLD proxy card that will revoke all prior proxy cards, including any White proxy cards which you may have submitted to Biogen; o instructing the Icahn Parties by telephone or via the Internet as to how you would like your shares voted (instructions are on your GOLD proxy card); o attending the Annual Meeting and withdrawing his or her proxy by voting in person (although attendance at the Annual Meeting will not in and of itself constitute revocation of a proxy); or o delivering written notice of revocation either to the Icahn Parties c/o Georgeson Inc., 199 Water Street, 26th Floor, New York, New York 10038, or the Corporate Secretary of Biogen. Although a revocation is effective if delivered to Biogen, the Icahn Parties request that either the original or a copy of any revocation be mailed to the Icahn Parties c/o Georgeson Inc., 199 Water Street, 26th Floor, New York, New York 10038, so that the Icahn Parties will be aware of all revocations. IF YOU PREVIOUSLY SIGNED AND RETURNED A WHITE PROXY CARD TO BIOGEN, WE URGE YOU TO REVOKE IT BY (1) MARKING, SIGNING, DATING AND RETURNING THE GOLD PROXY CARD, (2) INSTRUCTING US BY TELEPHONE OR VIA THE INTERNET AS TO HOW YOU WOULD LIKE YOUR SHARES VOTED WITH RESPECT TO THE GOLD PROXY CARD, (3) ATTENDING THE ANNUAL MEETING AND VOTING IN PERSON OR (4) DELIVERING A WRITTEN NOTICE OF REVOCATION TO THE ICAHN PARTIES OR TO THE CORPORATE SECRETARY OF THE COMPANY. COST AND METHOD OF SOLICITATION Solicitation of proxies shall be made by Messrs. Icahn, Denner, Meister, Intrieri and Schechter. The Icahn Parties have retained Georgeson Inc. ("Georgeson") to conduct the solicitation, for which Georgeson is to receive a fee not to exceed $350,000, plus reimbursement for its reasonable out-of-pocket expenses. The Icahn Parties have agreed to indemnify Georgeson against certain liabilities and expenses, including certain liabilities under the federal securities laws. Insofar as indemnification for liabilities arising under the federal securities laws may be permitted to Georgeson pursuant to the foregoing provisions, we have been informed, that in the opinion of the Securities and Exchange Commission, such indemnification is against public policy and is therefore unenforceable. Proxies may be solicited by mail, courier services, Internet, advertising, telephone or telecopier or in person. It is anticipated that Georgeson will employ approximately 60 persons to solicit proxies from Biogen Stockholders for the Annual Meeting. The total expenditures in furtherance of, or in connection with, the solicitation of proxies is approximately $75,000 to date, and is estimated to be $1.3 million in total. The Icahn Parties intend to seek reimbursement for the costs and expenses associated with the proxy solicitation in the event that any of the Nominees are elected to the Board of Directors of Biogen, but do not intend to submit the issue of reimbursement to a vote of security holders. ADDITIONAL INFORMATION Certain information regarding the securities of Biogen held by Biogen's directors, management and 5% Stockholders is contained in Biogen's Proxy Statement. Information concerning the date by which proposals of security holders intended to be presented at the next annual meeting of Stockholders of Biogen must be received by Biogen for inclusion in Biogen's Proxy Statement and form of proxy for that meeting is also contained in Biogen's Proxy Statement. This information is expected to be contained in Biogen's public filings. The Participants take no responsibility for the accuracy or completeness of such information contained in Biogen's public filings. Date: May 16, 2008 CARL C. ICAHN ALEXANDER J. DENNER ANNE B. YOUNG RICHARD C. MULLIGAN VINCENT J. INTRIERI KEITH A. MEISTER DAVID S. SCHECHTER ICAHN PARTNERS LP ICAHN PARTNERS MASTER FUND LP ICAHN PARTNERS MASTER FUND II LP ICAHN PARTNERS MASTER FUND III LP HIGH RIVER LIMITED PARTNERSHIP BARBERRY CORP. HOPPER INVESTMENTS LLC ICAHN OFFSHORE LP ICAHN ONSHORE LP ICAHN CAPITAL LP IPH GP LLC ICAHN ENTERPRISES HOLDINGS L.P. ICAHN ENTERPRISES G.P. INC. BECKTON CORP.

ANNEX A BENEFICIAL OWNERSHIP OF SECURITIES OF BIOGEN BENEFICIAL OWNERSHIP OF SECURITIES OF BIOGEN AS OF THE CLOSE OF BUSINESS ON MAY 16, 2008: (1) TITLE OF (2) NAME OF (3) BENEFICIAL (4) PERCENT OF CLASS (1) BENEFICIAL OWNERSHIP CLASS (3) OWNER(2) - -------------------------------------------------------------------------------- Common Stock, High River 2,487,181 0.85% par value $0.0005 per share - -------------------------------------------------------------------------------- Common Stock, Icahn Partners 3,736,220 1.28% par value $0.0005 per share - -------------------------------------------------------------------------------- Common Stock, Icahn Master 4,323,051 1.48% par value $0.0005 per share - -------------------------------------------------------------------------------- Common Stock, Icahn Master II 1,370,107 0.47% par value $0.0005 per share - -------------------------------------------------------------------------------- Common Stock, Icahn Master III 519,345 0.18% par value $0.0005 per share - -------------------------------------------------------------------------------- TOTAL 12,435,904 4.26% ____________________ (1) Please note that the Icahn Parties also purchased certain call options on Shares as described on Attachment 1 to this Annex A and wrote certain put options on Shares as described on Attachment 2 to this Annex A. All such call options were exercised on August 24, 2007. All such put options expired on August 24, 2007. (2) Please note that each Record Holder listed in this table is, as of the close of business on May 16, 2008, the direct beneficial owner of the Shares set forth under the heading "(3) Beneficial Ownership" and that indirect beneficial ownership of Shares is described below in the text of this Annex A under the heading "Description of Beneficial Ownership." (3) Please note that percentages of ownership set forth in this column were calculated based on the number of Shares stated to be outstanding as of April 21, 2008, as reported in Biogen's Proxy Statement filed on May 8, 2008.

INFORMATION ABOUT MR. ICAHN Mr. Icahn has an interest in the election of directors at the Annual Meeting indirectly through the beneficial ownership of securities, as described below. Carl C. Icahn, 72, has served as chairman of the board and a director of Starfire Holding Corporation, a privately-held holding company, and chairman of the board and a director of various subsidiaries of Starfire, since 1984. Since August 2007, through his position as Chief Executive Officer of Icahn Capital LP, a wholly owned subsidiary of Icahn Enterprises L.P., and certain related entities, Mr. Icahn's principal occupation is managing private investment funds, including Icahn Partners LP, Icahn Partners Master Fund LP, Icahn Partners Master Fund II LP and Icahn Partners Master Fund III LP. Prior to August 2007, Mr. Icahn conducted this occupation through his entities CCI Onshore Corp. and CCI Offshore Corp since September 2004. Since November 1990, Mr. Icahn has been chairman of the board of Icahn Enterprises G.P. Inc., the general partner of Icahn Enterprises L.P. Icahn Enterprises L.P. is a diversified holding company engaged in a variety of businesses, including investment management, metals, real estate and home fashion. Mr. Icahn was chairman of the board and president of Icahn & Co., Inc., a registered broker-dealer and a member of the National Association of Securities Dealers, from 1968 to 2005. Mr. Icahn has served as chairman of the board and as a director of American Railcar Industries, Inc., a company that is primarily engaged in the business of manufacturing covered hopper and tank railcars, since 1994. From October 1998 through May 2004, Mr. Icahn was the president and a director of Stratosphere Corporation, the owner and operator of the Stratosphere Hotel and Casino in Las Vegas, which until February 2008, was a subsidiary of Icahn Enterprises L.P. From September 2000 to February 2007, Mr. Icahn served as the chairman of the board of GB Holdings, Inc., which owned an interest in Atlantic Coast Holdings, Inc., the owner and operator of The Sands casino in Atlantic City until November 2006. Mr. Icahn has been chairman of the board and a director of XO Holdings, Inc., a telecommunications services provider, since February 2006 and of its predecessor from January 2003 to February 2006. Mr. Icahn has served as a Director of Cadus Corporation, a company engaged in the ownership and licensing of yeast-based drug discovery technologies since July 1993. In May 2005, Mr. Icahn became a director of Blockbuster Inc., a provider of in-home movie rental and game entertainment. In October 2005, Mr. Icahn became a director of WestPoint International, Inc., a manufacturer of bed and bath home fashion products. In September 2006, Mr. Icahn became a director of ImClone Systems Incorporated, a biopharmaceutical company, and since October 2006 has been the chairman of the board of ImClone Systems. In August 2007, Mr. Icahn became a director of WCI Communities, Inc., a homebuilding company, and since September 2007 has been the chairman of the board of WCI. In December 2007, Mr. Icahn became a director of Federal-Mogul Corporation, a supplier of automotive products, and since January 2008 has been the chairman of the board of Federal-Mogul. In April, 2008, Mr. Icahn became a director of Motricity, Inc., a company that provides mobile content services and solutions. Mr. Icahn received his B.A. from Princeton University. BENEFICIAL OWNERSHIP Barberry Corp., a Delaware corporation ("Barberry"), is the sole member of Hopper Investments LLC, a Delaware limited liability company ("Hopper"), which is the general partner of High River. Beckton Corp., a Delaware corporation ("Beckton") is the sole stockholder of Icahn Enterprises G.P. Inc., a Delaware corporation ("Icahn Enterprises GP"), which is the general partner of Icahn Enterprises Holdings L.P. ("Icahn Enterprises Holdings"). Icahn Enterprises Holdings is the sole member of IPH GP LLC, a Delaware limited liability company ("IPH"), which is the general partner of Icahn Capital LP, a Delaware limited partnership ("Icahn Capital"). Icahn Capital is the general partner of each of Icahn Onshore LP, a Delaware limited partnership ("Icahn Onshore") and Icahn Offshore LP, a Delaware limited partnership ("Icahn Offshore"). Icahn Onshore is the general partner of Icahn Partners. Icahn Offshore is the general partner of each of Icahn Master, Icahn Master II and Icahn Master III. Each of Barberry and Beckton is 100 percent owned by Carl C. Icahn. As such, Mr. Icahn is in a position indirectly to determine the investment and voting decisions made by each of High River, Icahn Partners, Icahn Master, Icahn Master II and Icahn Master III (collectively, the "Icahn Parties"). The Icahn Parties and Carl C. Icahn are deemed to beneficially own, in the aggregate, 12,435,904 Shares, representing approximately 4.26% of Biogen's outstanding Shares (based upon the 291,522,405 Shares stated to be outstanding as of April 21, 2008 by Biogen in Biogen's Proxy Statement.) High River has sole voting power and sole dispositive power with regard to 2,487,181 Shares. Each of Hopper, Barberry and Mr. Icahn has shared voting power and shared dispositive power with regard to such Shares. Icahn Partners has sole voting power and sole dispositive power with regard to 3,736,220 Shares. Each of Icahn Onshore, Icahn Capital, IPH, Icahn Enterprises Holdings, Icahn Enterprises GP, Beckton and Mr. Icahn has shared voting power and shared dispositive power with regard to such Shares. Icahn Master has sole voting power and sole dispositive power with regard to 4,323,051 Shares. Each of Icahn Offshore, Icahn Capital, IPH, Icahn Enterprises Holdings, Icahn Enterprises GP, Beckton and Mr. Icahn has shared voting power and shared dispositive power with regard to such Shares. Icahn Master II has sole voting power and sole dispositive power with regard to 1,370,107 Shares. Each of Icahn Offshore, Icahn Capital, IPH, Icahn Enterprises Holdings, Icahn Enterprises GP, Beckton and Mr. Icahn has shared voting power and shared dispositive power with regard to such Shares. Icahn Master III has sole voting power and sole dispositive power with regard to 519,345 Shares. Each of Icahn Offshore, Icahn Capital, IPH, Icahn Enterprises Holdings, Icahn Enterprises GP, Beckton and Mr. Icahn has shared voting power and shared dispositive power with regard to such Shares. Each of Hopper, Barberry and Mr. Icahn, by virtue of their relationships to High River, are deemed to beneficially own the Shares which High River directly beneficially owns. Each of Icahn Onshore, Icahn Capital, IPH, Icahn Enterprises Holdings, Icahn Enterprises GP, Beckton and Mr. Icahn, by virtue of their relationships to Icahn Partners, are deemed to beneficially own the Shares which Icahn Partners directly beneficially owns. Each of Icahn Offshore, Icahn Capital, IPH, Icahn Enterprises Holdings, Icahn Enterprises GP, Beckton and Mr. Icahn, by virtue of their relationships to Icahn Master, Icahn Master II and Icahn Master III, are deemed to beneficially own the Shares which Icahn Master, Icahn Master II and Icahn Master III directly beneficially own.

TWO YEAR SUMMARY TABLE The following table indicates the date of each purchase and sale of Shares, as well as the exercise of call options, by the Icahn Parties within the past two years, and the number of shares in each such purchase, sale, or call option exercise. NAME DATE SHARES PURCHASED/SOLD AND CALL OPTIONS EXERCISED(4) - -------------------------------------------------------------------------------- HIGH RIVER - -------------------------------------------------------------------------------- High River April 27, 2007 30,000 - -------------------------------------------------------------------------------- High River April 30, 2007 25,000 - -------------------------------------------------------------------------------- High River May 1, 2007 19,200 - -------------------------------------------------------------------------------- High River May 2, 2007 31,300 - -------------------------------------------------------------------------------- High River May 3, 2007 30,000 - -------------------------------------------------------------------------------- High River May 4, 2007 20,000 - -------------------------------------------------------------------------------- High River May 7, 2007 20 - -------------------------------------------------------------------------------- High River May 8, 2007 6,934 - -------------------------------------------------------------------------------- High River May 10, 2007 120,000 - -------------------------------------------------------------------------------- High River May 11, 2007 20,000 - -------------------------------------------------------------------------------- High River May 14, 2007 50,000 - -------------------------------------------------------------------------------- High River May 15, 2007 40,000 - -------------------------------------------------------------------------------- High River May 16, 2007 20,000 - -------------------------------------------------------------------------------- High River May 17, 2007 30,000 - -------------------------------------------------------------------------------- High River May 18, 2007 20,000 - -------------------------------------------------------------------------------- High River May 21, 2007 10,000 - -------------------------------------------------------------------------------- High River May 22, 2007 17,149 - -------------------------------------------------------------------------------- High River May 24, 2007 106,000 - -------------------------------------------------------------------------------- High River May 25, 2007 56,286 - -------------------------------------------------------------------------------- High River May 29, 2007 43,111 - -------------------------------------------------------------------------------- High River August 24, 2007 941,470 * - -------------------------------------------------------------------------------- High River August 24, 2007 943,952 ** - -------------------------------------------------------------------------------- High River September 6, 2007 (147,100) - -------------------------------------------------------------------------------- High River September 7, 2007 (55,240) - -------------------------------------------------------------------------------- High River September 10, 2007 (2,098) - -------------------------------------------------------------------------------- High River September 25, 2007 (109,000) - -------------------------------------------------------------------------------- High River September 26, 2007 (60,530) - -------------------------------------------------------------------------------- High River October 16, 2007 (64,020) - -------------------------------------------------------------------------------- High River October 16, 2007 (67,046) - -------------------------------------------------------------------------------- High River December 13, 2007 500,000 - -------------------------------------------------------------------------------- High River December 13, 2007 59,793 - -------------------------------------------------------------------------------- High River December 18, 2007 (113,660) - -------------------------------------------------------------------------------- High River December 19, 2007 (107,207) - -------------------------------------------------------------------------------- High River December 19, 2007 (46,133) - -------------------------------------------------------------------------------- High River December 20, 2007 (160,000) - -------------------------------------------------------------------------------- High River December 21, 2007 (124,000) - -------------------------------------------------------------------------------- High River December 24, 2007 (108,793) - -------------------------------------------------------------------------------- High River December 24, 2007 (11,207) - -------------------------------------------------------------------------------- High River January 24, 2008 33,000 - -------------------------------------------------------------------------------- High River January 25, 2008 390,000 - -------------------------------------------------------------------------------- ICAHN PARTNERS - -------------------------------------------------------------------------------- Icahn Partners April 27, 2007 38,293 - -------------------------------------------------------------------------------- Icahn Partners April 30, 2007 31,911 - -------------------------------------------------------------------------------- Icahn Partners May 1, 2007 24,186 - -------------------------------------------------------------------------------- Icahn Partners May 2, 2007 39,817 - -------------------------------------------------------------------------------- Icahn Partners May 3, 2007 38,165 - -------------------------------------------------------------------------------- Icahn Partners May 4, 2007 25,442 - -------------------------------------------------------------------------------- Icahn Partners May 7, 2007 26 - -------------------------------------------------------------------------------- Icahn Partners May 8, 2007 8,820 - -------------------------------------------------------------------------------- Icahn Partners May 10, 2007 152,654 - -------------------------------------------------------------------------------- Icahn Partners May 11, 2007 25,442 - -------------------------------------------------------------------------------- Icahn Partners May 14, 2007 63,606 - -------------------------------------------------------------------------------- Icahn Partners May 15, 2007 50,885 - -------------------------------------------------------------------------------- Icahn Partners May 16, 2007 25,443 - -------------------------------------------------------------------------------- Icahn Partners May 17, 2007 38,163 - -------------------------------------------------------------------------------- Icahn Partners May 18, 2007 25,443 - -------------------------------------------------------------------------------- Icahn Partners May 21, 2007 12,721 - -------------------------------------------------------------------------------- Icahn Partners May 22, 2007 21,815 - -------------------------------------------------------------------------------- Icahn Partners May 24, 2007 134,930 - -------------------------------------------------------------------------------- Icahn Partners May 25, 2007 71,611 - -------------------------------------------------------------------------------- Icahn Partners May 29, 2007 54,848 - -------------------------------------------------------------------------------- Icahn Partners August 24, 2007 1,214,776 * - -------------------------------------------------------------------------------- Icahn Partners August 24, 2007 1,218,780 ** - -------------------------------------------------------------------------------- Icahn Partners September 7, 2007 (54,463) - -------------------------------------------------------------------------------- Icahn Partners September 10, 2007 (2,878) - -------------------------------------------------------------------------------- Icahn Partners September 25, 2007 (149,338) - -------------------------------------------------------------------------------- Icahn Partners September 26, 2007 (83,068) - -------------------------------------------------------------------------------- Icahn Partners October 16, 2007 (22,510) - -------------------------------------------------------------------------------- Icahn Partners December 13, 2007 754,630 - -------------------------------------------------------------------------------- Icahn Partners December 13, 2007 367,948 - -------------------------------------------------------------------------------- Icahn Partners December 18, 2007 (171,544) - -------------------------------------------------------------------------------- Icahn Partners December 19, 2007 (196,404) - -------------------------------------------------------------------------------- Icahn Partners December 19, 2007 (35,027) - -------------------------------------------------------------------------------- Icahn Partners December 20, 2007 (241,481) - -------------------------------------------------------------------------------- Icahn Partners December 21, 2007 (187,148) - -------------------------------------------------------------------------------- Icahn Partners December 24, 2007 (181,111) - -------------------------------------------------------------------------------- Icahn Partners January 24, 2008 34,982 - -------------------------------------------------------------------------------- Icahn Partners January 25, 2008 585,855 - -------------------------------------------------------------------------------- ICAHN MASTER - -------------------------------------------------------------------------------- Icahn Master April 27, 2007 55,094 - -------------------------------------------------------------------------------- Icahn Master April 30, 2007 45,911 - -------------------------------------------------------------------------------- Icahn Master May 1, 2007 36,875 - -------------------------------------------------------------------------------- Icahn Master May 2, 2007 58,162 - -------------------------------------------------------------------------------- Icahn Master May 3, 2007 55,738 - -------------------------------------------------------------------------------- Icahn Master May 4, 2007 37,163 - -------------------------------------------------------------------------------- Icahn Master May 7, 2007 38 - -------------------------------------------------------------------------------- Icahn Master May 8, 2007 12,883 - -------------------------------------------------------------------------------- Icahn Master May 10, 2007 222,979 - -------------------------------------------------------------------------------- Icahn Master May 11, 2007 37,163 - -------------------------------------------------------------------------------- Icahn Master May 14, 2007 92,908 - -------------------------------------------------------------------------------- Icahn Master May 15, 2007 74,327 - -------------------------------------------------------------------------------- Icahn Master May 16, 2007 37,163 - -------------------------------------------------------------------------------- Icahn Master May 17, 2007 55,744 - -------------------------------------------------------------------------------- Icahn Master May 18, 2007 37,164 - -------------------------------------------------------------------------------- Icahn Master May 21, 2007 18,581 - -------------------------------------------------------------------------------- Icahn Master May 22, 2007 31,866 - -------------------------------------------------------------------------------- Icahn Master May 24, 2007 196,907 - -------------------------------------------------------------------------------- Icahn Master May 25, 2007 104,585 - -------------------------------------------------------------------------------- Icahn Master May 29, 2007 80,102 - -------------------------------------------------------------------------------- Icahn Master August 24, 2007 1,747,975 * - -------------------------------------------------------------------------------- Icahn Master August 24, 2007 1,776,777 ** - -------------------------------------------------------------------------------- Icahn Master September 6, 2007 (405,705) - -------------------------------------------------------------------------------- Icahn Master September 7, 2007 (114,462) - -------------------------------------------------------------------------------- Icahn Master September 10, 2007 (3,789) - -------------------------------------------------------------------------------- Icahn Master September 25, 2007 (197,537) - -------------------------------------------------------------------------------- Icahn Master September 26, 2007 (109,329) - -------------------------------------------------------------------------------- Icahn Master October 16, 2007 (170,708) - -------------------------------------------------------------------------------- Icahn Master October 16, 2007 (169,108) - -------------------------------------------------------------------------------- Icahn Master December 13, 2007 862,247 - -------------------------------------------------------------------------------- Icahn Master December 13, 2007 209,093 - -------------------------------------------------------------------------------- Icahn Master December 18, 2007 (196,006) - -------------------------------------------------------------------------------- Icahn Master December 19, 2007 (13,087) - -------------------------------------------------------------------------------- Icahn Master December 19, 2007 (251,347) - -------------------------------------------------------------------------------- Icahn Master December 20, 2007 (275,919) - -------------------------------------------------------------------------------- Icahn Master December 21, 2007 (213,838) - -------------------------------------------------------------------------------- Icahn Master December 24, 2007 (121,143) - -------------------------------------------------------------------------------- Icahn Master December 24, 2007 ( 80,102) - -------------------------------------------------------------------------------- Icahn Master December 24, 2007 ( 5,694) - -------------------------------------------------------------------------------- Icahn Master January 24, 2008 85,509 - -------------------------------------------------------------------------------- Icahn Master January 25, 2008 677,871 - -------------------------------------------------------------------------------- ICAHN MASTER II - -------------------------------------------------------------------------------- Icahn Master II April 27, 2007 19,109 - -------------------------------------------------------------------------------- Icahn Master II April 30, 2007 15,923 - -------------------------------------------------------------------------------- Icahn Master II May 1, 2007 11,656 - -------------------------------------------------------------------------------- Icahn Master II May 2, 2007 19,693 - -------------------------------------------------------------------------------- Icahn Master II May 3, 2007 18,876 - -------------------------------------------------------------------------------- Icahn Master II May 4, 2007 12,584 - -------------------------------------------------------------------------------- Icahn Master II May 7, 2007 12 - -------------------------------------------------------------------------------- Icahn Master II May 8, 2007 4,363 - -------------------------------------------------------------------------------- Icahn Master II May 10, 2007 75,504 - -------------------------------------------------------------------------------- Icahn Master II May 11, 2007 12,584 - -------------------------------------------------------------------------------- Icahn Master II May 14, 2007 31,461 - -------------------------------------------------------------------------------- Icahn Master II May 15, 2007 25,167 - -------------------------------------------------------------------------------- Icahn Master II May 16, 2007 12,585 - -------------------------------------------------------------------------------- Icahn Master II May 17, 2007 18,876 - -------------------------------------------------------------------------------- Icahn Master II May 18, 2007 12,584 - -------------------------------------------------------------------------------- Icahn Master II May 21, 2007 6,292 - -------------------------------------------------------------------------------- Icahn Master II May 22, 2007 10,790 - -------------------------------------------------------------------------------- Icahn Master II May 24, 2007 66,766 - -------------------------------------------------------------------------------- Icahn Master II May 25, 2007 35,422 - -------------------------------------------------------------------------------- Icahn Master II May 29, 2007 27,131 - -------------------------------------------------------------------------------- Icahn Master II August 24, 2007 583,382 * - -------------------------------------------------------------------------------- Icahn Master II August 24, 2007 566,437 ** - -------------------------------------------------------------------------------- Icahn Master II September 6, 2007 (132,473) - -------------------------------------------------------------------------------- Icahn Master II September 7, 2007 (37,752) - -------------------------------------------------------------------------------- Icahn Master II September 10, 2007 (1,250) - -------------------------------------------------------------------------------- Icahn Master II September 25, 2007 (64,548) - -------------------------------------------------------------------------------- Icahn Master II September 26, 2007 (36,077) - -------------------------------------------------------------------------------- Icahn Master II October 16, 2007 (62,115) - -------------------------------------------------------------------------------- Icahn Master II October 16, 2007 (55,546) - -------------------------------------------------------------------------------- Icahn Master II December 13, 2007 277,956 - -------------------------------------------------------------------------------- Icahn Master II December 13, 2007 45,129 - -------------------------------------------------------------------------------- Icahn Master II December 18, 2007 (18,055) - -------------------------------------------------------------------------------- Icahn Master II December 18, 2007 (45,129) - -------------------------------------------------------------------------------- Icahn Master II December 19, 2007 (85,243) - -------------------------------------------------------------------------------- Icahn Master II December 20, 2007 (88,947) - -------------------------------------------------------------------------------- Icahn Master II December 21, 2007 (68,933) - -------------------------------------------------------------------------------- Icahn Master II December 24, 2007 (16,778) - -------------------------------------------------------------------------------- Icahn Master II December 24, 2007 (27,131) - -------------------------------------------------------------------------------- Icahn Master II December 24, 2007 (22,801) - -------------------------------------------------------------------------------- Icahn Master II January 24, 2008 7,764 - -------------------------------------------------------------------------------- Icahn Master II January 25, 2008 214,839 - -------------------------------------------------------------------------------- ICAHN MASTER III - -------------------------------------------------------------------------------- Icahn Master III April 27, 2007 7,504 - -------------------------------------------------------------------------------- Icahn Master III April 30, 2007 6,255 - -------------------------------------------------------------------------------- Icahn Master III May 1, 2007 4,083 - -------------------------------------------------------------------------------- Icahn Master III May 2, 2007 7,528 - -------------------------------------------------------------------------------- Icahn Master III May 3, 2007 7,221 - -------------------------------------------------------------------------------- Icahn Master III May 4, 2007 4,811 - -------------------------------------------------------------------------------- Icahn Master III May 7, 2007 4 - -------------------------------------------------------------------------------- Icahn Master III May 8, 2007 1,668 - -------------------------------------------------------------------------------- Icahn Master III May 10, 2007 28,863 - -------------------------------------------------------------------------------- Icahn Master III May 11, 2007 4,811 - -------------------------------------------------------------------------------- Icahn Master III May 14, 2007 12,025 - -------------------------------------------------------------------------------- Icahn Master III May 15, 2007 9,621 - -------------------------------------------------------------------------------- Icahn Master III May 16, 2007 4,809 - -------------------------------------------------------------------------------- Icahn Master III May 17, 2007 7,217 - -------------------------------------------------------------------------------- Icahn Master III May 18, 2007 4,809 - -------------------------------------------------------------------------------- Icahn Master III May 21, 2007 2,406 - -------------------------------------------------------------------------------- Icahn Master III May 22, 2007 4,125 - -------------------------------------------------------------------------------- Icahn Master III May 24, 2007 25,397 - -------------------------------------------------------------------------------- Icahn Master III May 25, 2007 13,529 - -------------------------------------------------------------------------------- Icahn Master III May 29, 2007 10,362 - -------------------------------------------------------------------------------- Icahn Master III August 24, 2007 219,750 * - -------------------------------------------------------------------------------- Icahn Master III August 24, 2007 213,810 ** - -------------------------------------------------------------------------------- Icahn Master III September 6, 2007 (50,222) - -------------------------------------------------------------------------------- Icahn Master III September 7, 2007 (14,283) - -------------------------------------------------------------------------------- Icahn Master III September 10, 2007 (473) - -------------------------------------------------------------------------------- Icahn Master III September 25, 2007 (24,577) - -------------------------------------------------------------------------------- Icahn Master III September 26, 2007 (13,647) - -------------------------------------------------------------------------------- Icahn Master III October 16, 2007 (23,257) - -------------------------------------------------------------------------------- Icahn Master III October 16, 2007 (21,021) - -------------------------------------------------------------------------------- Icahn Master III December 13, 2007 105,167 - -------------------------------------------------------------------------------- Icahn Master III December 13, 2007 17,002 - -------------------------------------------------------------------------------- Icahn Master III December 18, 2007 (6,904) - -------------------------------------------------------------------------------- Icahn Master III December 18, 2007 (17,002) - -------------------------------------------------------------------------------- Icahn Master III December 19, 2007 (32,252) - -------------------------------------------------------------------------------- Icahn Master III December 20, 2007 (33,653) - -------------------------------------------------------------------------------- Icahn Master III December 21, 2007 (26,081) - -------------------------------------------------------------------------------- Icahn Master III December 24, 2007 (6,277) - -------------------------------------------------------------------------------- Icahn Master III December 24, 2007 (10,362) - -------------------------------------------------------------------------------- Icahn Master III December 24, 2007 (8,601) - -------------------------------------------------------------------------------- Icahn Master III January 24, 2008 3,745 - -------------------------------------------------------------------------------- Icahn Master III January 25, 2008 81,435 - -------------------------------------------------------------------------------- ____________________ (4) Sales of Shares in this column are indicated by the use of a parenthetical. * These amounts consist of Shares obtained by the respective Icahn Party as a result of an exercise by such party of its call options written by Merrill Lynch International, which had a strike price of $35.50 and an expiration date of November 26, 2008 (which options were purchased by the Icahn Parties as described on Attachment 1 to this Annex A), and the dates set forth in the table above with respect to such Shares are the dates on which such options were exercised. ** These amounts consist of Shares obtained by the respective Icahn Party as a result of an exercise by such party of its call options written by UBS AG, which had a strike price of $31.50 and an expiration date of November 26, 2008 (which options were purchased by the Icahn Parties as described on Attachment 1 to this Annex A), and the dates set forth in the table above with respect to such Shares are the dates on which such options were exercised. Part of the purchase price of Shares purchased by High River was obtained through margin borrowing. Shares purchased by High River are maintained in a margin account that includes positions in securities in addition to the Shares. The indebtedness of the margin account as of May 15, 2008 was approximately $1.1 billion.

ATTACHMENT 1 TO ANNEX A Call options purchased by the Icahn Parties, which were written by UBS AG and have a $31.50 strike price, expiration date of November 26, 2008, and are further described in the chart set forth below. On August 24, 2007, the Icahn Parties exercised all of the call options described in the chart below and thereby acquired the Shares covered by such options. NAME DATE NUMBER OF OPTION SHARES SUBJECT PREMIUM TO OPTION ($) - -------------------------------------------------------------------------------- HIGH RIVER - -------------------------------------------------------------------------------- High River May 29, 2007 50,000 872,885.00 - -------------------------------------------------------------------------------- High River May 31, 2007 85,760 1,772,050.30 - -------------------------------------------------------------------------------- High River June 1, 2007 74,000 1,532,014.60 - -------------------------------------------------------------------------------- High River June 4, 2007 40,000 822,144.00 - -------------------------------------------------------------------------------- High River June 8, 2007 81,151 1,619,295.17 - -------------------------------------------------------------------------------- High River June 11, 2007 20,000 399,928.00 - -------------------------------------------------------------------------------- High River June 12, 2007 27,765 543,258.32 - -------------------------------------------------------------------------------- High River June 13, 2007 54,976 1,088,150.96 - -------------------------------------------------------------------------------- High River June 14, 2007 40,000 796,540.00 - -------------------------------------------------------------------------------- High River June 27, 2007 43,600 936,092.00 - -------------------------------------------------------------------------------- High River June 28, 2007 100,000 2,203,950.00 - -------------------------------------------------------------------------------- High River June 29, 2007 100,000 2,203,370.00 - -------------------------------------------------------------------------------- High River July 2, 2007 53,100 1,164,259.98 - -------------------------------------------------------------------------------- High River July 9, 2007 25,400 587,283.56 - -------------------------------------------------------------------------------- High River July 10, 2007 11,200 258,709.92 - -------------------------------------------------------------------------------- High River July 16, 2007 50,000 1,197,000.00 - -------------------------------------------------------------------------------- High River July 17, 2007 87,000 2,058,367.80 - -------------------------------------------------------------------------------- ICAHN PARTNERS - -------------------------------------------------------------------------------- Icahn Partners May 29, 2007 63,614 1,110,554.13 - -------------------------------------------------------------------------------- Icahn Partners May 31, 2007 109,109 2,254,508.36 - -------------------------------------------------------------------------------- Icahn Partners June 1, 2007 97,229 2,012,922.26 - -------------------------------------------------------------------------------- Icahn Partners June 4, 2007 50,954 1,047,288.13 - -------------------------------------------------------------------------------- Icahn Partners June 8, 2007 103,652 2,068,282.37 - -------------------------------------------------------------------------------- Icahn Partners June 11, 2007 25,514 510,188.15 - -------------------------------------------------------------------------------- Icahn Partners June 12, 2007 35,420 693,038.35 - -------------------------------------------------------------------------------- Icahn Partners June 13, 2007 70,134 1,388,176.29 - -------------------------------------------------------------------------------- Icahn Partners June 14, 2007 51,030 1,016,185.91 - -------------------------------------------------------------------------------- Icahn Partners June 27, 2007 55,631 1,194,397.57 - -------------------------------------------------------------------------------- Icahn Partners June 28, 2007 127,574 2,811,667.17 - -------------------------------------------------------------------------------- Icahn Partners June 29, 2007 127,574 2,810,927.24 - -------------------------------------------------------------------------------- Icahn Partners July 2, 2007 64,783 1,420,419.10 - -------------------------------------------------------------------------------- Icahn Partners July 9, 2007 46,401 1,072,856.08 - -------------------------------------------------------------------------------- Icahn Partners July 10, 2007 14,370 331,934.07 - -------------------------------------------------------------------------------- Icahn Partners July 16, 2007 64,157 1,535,918.58 - -------------------------------------------------------------------------------- Icahn Partners July 17, 2007 111,634 2,641,193.46 - -------------------------------------------------------------------------------- ICAHN MASTER - -------------------------------------------------------------------------------- Icahn Master May 29, 2007 92,903 1,621,872.70 - -------------------------------------------------------------------------------- Icahn Master May 31, 2007 159,347 3,292,571.13 - -------------------------------------------------------------------------------- Icahn Master June 1, 2007 152,205 3,151,084.89 - -------------------------------------------------------------------------------- Icahn Master June 4, 2007 75,113 1,543,842.56 - -------------------------------------------------------------------------------- Icahn Master June 8, 2007 152,235 3,037,712.41 - -------------------------------------------------------------------------------- Icahn Master June 11, 2007 37,492 749,705.03 - -------------------------------------------------------------------------------- Icahn Master June 12, 2007 52,047 1,018,367.22 - -------------------------------------------------------------------------------- Icahn Master June 13, 2007 103,056 2,039,808.02 - -------------------------------------------------------------------------------- Icahn Master June 14, 2007 74,984 1,493,193.88 - -------------------------------------------------------------------------------- Icahn Master June 27, 2007 81,792 1,756,074.24 - -------------------------------------------------------------------------------- Icahn Master June 28, 2007 187,463 4,131,590.79 - -------------------------------------------------------------------------------- Icahn Master June 29, 2007 187,464 4,130,525.54 - -------------------------------------------------------------------------------- Icahn Master July 2, 2007 110,439 2,421,463.43 - -------------------------------------------------------------------------------- Icahn Master July 9, 2007 32,806 758,520.65 - -------------------------------------------------------------------------------- Icahn Master July 10, 2007 20,966 484,295.73 - -------------------------------------------------------------------------------- Icahn Master July 16, 2007 93,601 2,240,807.94 - -------------------------------------------------------------------------------- Icahn Master July 17, 2007 162,864 3,853,264.52 - -------------------------------------------------------------------------------- ICAHN MASTER II - -------------------------------------------------------------------------------- Icahn Master II May 29, 2007 31,465 549,306.53 - -------------------------------------------------------------------------------- Icahn Master II May 31, 2007 53,972 1,115,218.04 - -------------------------------------------------------------------------------- Icahn Master II June 1, 2007 34,144 706,879.82 - -------------------------------------------------------------------------------- Icahn Master II June 4, 2007 24,577 505,145.83 - -------------------------------------------------------------------------------- Icahn Master II June 8, 2007 49,762 992,955.92 - -------------------------------------------------------------------------------- Icahn Master II June 11, 2007 12,308 246,115.69 - -------------------------------------------------------------------------------- Icahn Master II June 12, 2007 17,085 334,290.24 - -------------------------------------------------------------------------------- Icahn Master II June 13, 2007 33,830 669,603.96 - -------------------------------------------------------------------------------- Icahn Master II June 14, 2007 24,614 490,150.89 - -------------------------------------------------------------------------------- Icahn Master II June 27, 2007 26,772 574,794.84 - -------------------------------------------------------------------------------- Icahn Master II June 28, 2007 61,531 1,356,112.47 - -------------------------------------------------------------------------------- Icahn Master II June 29, 2007 61,530 1,355,733.56 - -------------------------------------------------------------------------------- Icahn Master II July 2, 2007 27,772 608,923.32 - -------------------------------------------------------------------------------- Icahn Master II July 9, 2007 16,307 377,040.67 - -------------------------------------------------------------------------------- Icahn Master II July 10, 2007 6,860 158,459.83 - -------------------------------------------------------------------------------- Icahn Master II July 16, 2007 30,623 733,114.62 - -------------------------------------------------------------------------------- Icahn Master II July 17, 2007 53,285 1,260,691.13 - -------------------------------------------------------------------------------- ICAHN MASTER III - -------------------------------------------------------------------------------- Icahn Master III May 29, 2007 12,018 209,806.64 - -------------------------------------------------------------------------------- Icahn Master III May 31, 2007 20,612 425,903.69 - -------------------------------------------------------------------------------- Icahn Master III June 1, 2007 12,422 257,171.42 - -------------------------------------------------------------------------------- Icahn Master III June 4, 2007 9,356 192,299.48 - -------------------------------------------------------------------------------- Icahn Master III June 8, 2007 18,953 378,190.06 - -------------------------------------------------------------------------------- Icahn Master III June 11, 2007 4,686 93,703.13 - -------------------------------------------------------------------------------- Icahn Master III June 12, 2007 6,507 127,317.91 - -------------------------------------------------------------------------------- Icahn Master III June 13, 2007 12,883 254,995.80 - -------------------------------------------------------------------------------- Icahn Master III June 14, 2007 9,372 186,629.32 - -------------------------------------------------------------------------------- Icahn Master III June 27, 2007 10,205 219,101.35 - -------------------------------------------------------------------------------- Icahn Master III June 28, 2007 23,432 516,429.56 - -------------------------------------------------------------------------------- Icahn Master III June 29, 2007 23,432 516,293.66 - -------------------------------------------------------------------------------- Icahn Master III July 2, 2007 9,406 206,234.07 - -------------------------------------------------------------------------------- Icahn Master III July 9, 2007 6,086 140,716.84 - -------------------------------------------------------------------------------- Icahn Master III July 10, 2007 2,604 60,150.06 - -------------------------------------------------------------------------------- Icahn Master III July 16, 2007 11,619 278,158.86 - -------------------------------------------------------------------------------- Icahn Master III July 17, 2007 20,217 478,322.09 - --------------------------------------------------------------------------------

Call options purchased by the Icahn Parties, which were written by Merrill Lynch International and have a $35.50 strike price, expiration date of November 26, 2008, and are further described in the chart set forth below. On August 24, 2007, the Icahn Parties exercised all of the call options described in the chart below and thereby acquired the Shares covered by such options. NAME DATE NUMBER OF OPTION SHARES SUBJECT PREMIUM TO OPTION ($) - -------------------------------------------------------------------------------- HIGH RIVER - -------------------------------------------------------------------------------- High River July 10, 2007 102,929 1,965,665.99 - -------------------------------------------------------------------------------- High River July 11, 2007 30,536 582,388.70 - -------------------------------------------------------------------------------- High River July 12, 2007 57,192 1,100,545.66 - -------------------------------------------------------------------------------- High River July 18, 2007 200,000 3,795,760.00 - -------------------------------------------------------------------------------- High River July 19, 2007 159,233 3,082,320.95 - -------------------------------------------------------------------------------- High River July 20, 2007 71,580 1,377,929.32 - -------------------------------------------------------------------------------- High River July 23, 2007 120,000 2,290,056.00 - -------------------------------------------------------------------------------- High River July 31, 2007 94,969 1,978,356.22 - -------------------------------------------------------------------------------- High River August 1, 2007 105,031 2,213,633.36 - -------------------------------------------------------------------------------- ICAHN PARTNERS - -------------------------------------------------------------------------------- Icahn Partners July 10, 2007 132,074 2,522,256.80 - -------------------------------------------------------------------------------- Icahn Partners July 11, 2007 39,181 747,267.87 - -------------------------------------------------------------------------------- Icahn Partners July 12, 2007 73,385 1,412,147.56 - -------------------------------------------------------------------------------- Icahn Partners July 18, 2007 256,627 4,870,472.51 - -------------------------------------------------------------------------------- Icahn Partners July 19, 2007 204,318 3,955,044.82 - -------------------------------------------------------------------------------- Icahn Partners July 20, 2007 91,847 1,768,073.12 - -------------------------------------------------------------------------------- Icahn Partners July 23, 2007 153,977 2,938,466.27 - -------------------------------------------------------------------------------- Icahn Partners July 31, 2007 121,987 2,541,184.39 - -------------------------------------------------------------------------------- Icahn Partners August 1, 2007 141,380 2,979,724.88 - -------------------------------------------------------------------------------- ICAHN MASTER - -------------------------------------------------------------------------------- Icahn Master July 10, 2007 192,685 3,679,763.25 - -------------------------------------------------------------------------------- Icahn Master July 11, 2007 57,163 1,090,224.17 - -------------------------------------------------------------------------------- Icahn Master July 12, 2007 107,064 2,060,232.55 - -------------------------------------------------------------------------------- Icahn Master July 18, 2007 374,402 7,105,700.68 - -------------------------------------------------------------------------------- Icahn Master July 19, 2007 298,086 5,770,140.13 - -------------------------------------------------------------------------------- Icahn Master July 20, 2007 133,999 2,579,507.55 - -------------------------------------------------------------------------------- Icahn Master July 23, 2007 224,640 4,286,984.83 - -------------------------------------------------------------------------------- Icahn Master July 31, 2007 177,800 3,703,858.48 - -------------------------------------------------------------------------------- Icahn Master August 1, 2007 182,136 3,838,698.34 - -------------------------------------------------------------------------------- ICAHN MASTER II - -------------------------------------------------------------------------------- Icahn Master II July 10, 2007 63,042 1,203,931.99 - -------------------------------------------------------------------------------- Icahn Master II July 11, 2007 18,702 356,688.28 - -------------------------------------------------------------------------------- Icahn Master II July 12, 2007 35,029 674,063.05 - -------------------------------------------------------------------------------- Icahn Master II July 18, 2007 122,495 2,324,808.11 - -------------------------------------------------------------------------------- Icahn Master II July 19, 2007 97,526 1,887,840.04 - -------------------------------------------------------------------------------- Icahn Master II July 20, 2007 43,842 843,967.27 - -------------------------------------------------------------------------------- Icahn Master II July 23, 2007 73,498 1,402,621.13 - -------------------------------------------------------------------------------- Icahn Master II July 31, 2007 58,078 1,209,857.66 - -------------------------------------------------------------------------------- Icahn Master II August 1, 2007 71,170 1,499,978.92 - -------------------------------------------------------------------------------- ICAHN MASTER III - -------------------------------------------------------------------------------- Icahn Master III July 10, 2007 23,917 456,750.12 - -------------------------------------------------------------------------------- Icahn Master III July 11, 2007 7,097 135,355.40 - -------------------------------------------------------------------------------- Icahn Master III July 12, 2007 13,290 255,739.47 - -------------------------------------------------------------------------------- Icahn Master III July 18, 2007 46,476 882,058.71 - -------------------------------------------------------------------------------- Icahn Master III July 19, 2007 37,004 716,297.53 - -------------------------------------------------------------------------------- Icahn Master III July 20, 2007 16,632 320,169.33 - -------------------------------------------------------------------------------- Icahn Master III July 23, 2007 27,885 532,151.76 - -------------------------------------------------------------------------------- Icahn Master III July 31, 2007 22,013 458,566.01 - -------------------------------------------------------------------------------- Icahn Master III August 1, 2007 25,436 536,089.14 - --------------------------------------------------------------------------------

ATTACHMENT 2 TO ANNEX A Put options purchased by the Icahn Parties, which were written by UBS AG and had a $31.50 strike price, expiration date of November 26, 2008, and provided for cash settlement only and for exercise only at expiration are further described in the chart set forth below. All of the put options described below terminated on August 24, 2007. NAME DATE NUMBER OF OPTION SHARES SUBJECT PREMIUM TO OPTION ($) - -------------------------------------------------------------------------------- HIGH RIVER - -------------------------------------------------------------------------------- High River May 29, 2007 50,000 500.00 - -------------------------------------------------------------------------------- High River May 31, 2007 85,760 857.60 - -------------------------------------------------------------------------------- High River June 1, 2007 74,000 740.00 - -------------------------------------------------------------------------------- High River June 4, 2007 40,000 400.00 - -------------------------------------------------------------------------------- High River June 8, 2007 81,151 811.51 - -------------------------------------------------------------------------------- High River June 11, 2007 20,000 200.00 - -------------------------------------------------------------------------------- High River June 12, 2007 27,765 277.65 - -------------------------------------------------------------------------------- High River June 13, 2007 54,976 549.76 - -------------------------------------------------------------------------------- High River June 14, 2007 40,000 400.00 - -------------------------------------------------------------------------------- High River June 27, 2007 43,600 436.00 - -------------------------------------------------------------------------------- High River June 28, 2007 100,000 1,000.00 - -------------------------------------------------------------------------------- High River June 29, 2007 100,000 1,000.00 - -------------------------------------------------------------------------------- High River July 2, 2007 53,100 531.00 - -------------------------------------------------------------------------------- High River July 9, 2007 25,400 254.00 - -------------------------------------------------------------------------------- High River July 10, 2007 11,200 112.00 - -------------------------------------------------------------------------------- High River July 16, 2007 50,000 500.00 - -------------------------------------------------------------------------------- High River July 17, 2007 87,000 870.00 - -------------------------------------------------------------------------------- ICAHN PARTNERS - -------------------------------------------------------------------------------- Icahn Partners May 29, 2007 63,614 636.14 - -------------------------------------------------------------------------------- Icahn Partners May 31, 2007 109,109 1,091.09 - -------------------------------------------------------------------------------- Icahn Partners June 1, 2007 97,229 972.29 - -------------------------------------------------------------------------------- Icahn Partners June 4, 2007 50,954 509.54 - -------------------------------------------------------------------------------- Icahn Partners June 8, 2007 103,652 1,036.52 - -------------------------------------------------------------------------------- Icahn Partners June 11, 2007 25,514 255.14 - -------------------------------------------------------------------------------- Icahn Partners June 12, 2007 35,420 354.20 - -------------------------------------------------------------------------------- Icahn Partners June 13, 2007 70,134 701.34 - -------------------------------------------------------------------------------- Icahn Partners June 14, 2007 51,030 510.30 - -------------------------------------------------------------------------------- Icahn Partners June 27, 2007 55,631 556.31 - -------------------------------------------------------------------------------- Icahn Partners June 28, 2007 127,574 1,275.74 - -------------------------------------------------------------------------------- Icahn Partners June 29, 2007 127,574 1,275.74 - -------------------------------------------------------------------------------- Icahn Partners July 2, 2007 64,783 647.83 - -------------------------------------------------------------------------------- Icahn Partners July 9, 2007 46,401 464.01 - -------------------------------------------------------------------------------- Icahn Partners July 10, 2007 14,370 143.70 - -------------------------------------------------------------------------------- Icahn Partners July 16, 2007 64,157 641.57 - -------------------------------------------------------------------------------- Icahn Partners July 17, 2007 111,634 1,116.34 - -------------------------------------------------------------------------------- ICAHN MASTER - -------------------------------------------------------------------------------- Icahn Master May 29, 2007 92,903 929.03 - -------------------------------------------------------------------------------- Icahn Master May 31, 2007 159,347 1,593.47 - -------------------------------------------------------------------------------- Icahn Master June 1, 2007 152,205 1,522.05 - -------------------------------------------------------------------------------- Icahn Master June 4, 2007 75,113 751.13 - -------------------------------------------------------------------------------- Icahn Master June 8, 2007 152,235 1,522.35 - -------------------------------------------------------------------------------- Icahn Master June 11, 2007 37,492 374.92 - -------------------------------------------------------------------------------- Icahn Master June 12, 2007 52,047 520.47 - -------------------------------------------------------------------------------- Icahn Master June 13, 2007 103,056 1,030.56 - -------------------------------------------------------------------------------- Icahn Master June 14, 2007 74,984 749.84 - -------------------------------------------------------------------------------- Icahn Master June 27, 2007 81,792 817.92 - -------------------------------------------------------------------------------- Icahn Master June 28, 2007 187,463 1,874.63 - -------------------------------------------------------------------------------- Icahn Master June 29, 2007 187,464 1,874.64 - -------------------------------------------------------------------------------- Icahn Master July 2, 2007 110,439 1,104.39 - -------------------------------------------------------------------------------- Icahn Master July 9, 2007 32,806 328.06 - -------------------------------------------------------------------------------- Icahn Master July 10, 2007 20,966 209.66 - -------------------------------------------------------------------------------- Icahn Master July 16, 2007 93,601 936.01 - -------------------------------------------------------------------------------- Icahn Master July 17, 2007 162,864 1,628.64 - -------------------------------------------------------------------------------- ICAHN MASTER II - -------------------------------------------------------------------------------- Icahn Master II May 29, 2007 31,465 314.65 - -------------------------------------------------------------------------------- Icahn Master II May 31, 2007 53,972 539.72 - -------------------------------------------------------------------------------- Icahn Master II June 1, 2007 34,144 341.44 - -------------------------------------------------------------------------------- Icahn Master II June 4, 2007 24,577 245.77 - -------------------------------------------------------------------------------- Icahn Master II June 8, 2007 49,762 497.62 - -------------------------------------------------------------------------------- Icahn Master II June 11, 2007 12,308 123.08 - -------------------------------------------------------------------------------- Icahn Master II June 12, 2007 17,085 170.85 - -------------------------------------------------------------------------------- Icahn Master II June 13, 2007 33,830 338.30 - -------------------------------------------------------------------------------- Icahn Master II June 14, 2007 24,614 246.14 - -------------------------------------------------------------------------------- Icahn Master II June 27, 2007 26,772 267.72 - -------------------------------------------------------------------------------- Icahn Master II June 28, 2007 61,531 615.31 - -------------------------------------------------------------------------------- Icahn Master II June 29, 2007 61,530 615.30 - -------------------------------------------------------------------------------- Icahn Master II July 2, 2007 27,772 277.72 - -------------------------------------------------------------------------------- Icahn Master II July 9, 2007 16,307 163.07 - -------------------------------------------------------------------------------- Icahn Master II July 10, 2007 6,860 68.60 - -------------------------------------------------------------------------------- Icahn Master II July 16, 2007 30,623 306.23 - -------------------------------------------------------------------------------- ICAHN MASTER III - -------------------------------------------------------------------------------- Icahn Master III May 29, 2007 12,018 120.18 - -------------------------------------------------------------------------------- Icahn Master III May 31, 2007 20,612 206.12 - -------------------------------------------------------------------------------- Icahn Master III June 1, 2007 12,422 124.22 - -------------------------------------------------------------------------------- Icahn Master III June 4, 2007 9,356 93.56 - -------------------------------------------------------------------------------- Icahn Master III June 8, 2007 18,953 189.53 - -------------------------------------------------------------------------------- Icahn Master III June 11, 2007 4,686 46.86 - -------------------------------------------------------------------------------- Icahn Master III June 12, 2007 6,507 65.07 - -------------------------------------------------------------------------------- Icahn Master III June 13, 2007 12,883 128.83 - -------------------------------------------------------------------------------- Icahn Master III June 14, 2007 9,372 93.72 - -------------------------------------------------------------------------------- Icahn Master III June 27, 2007 10,205 102.05 - -------------------------------------------------------------------------------- Icahn Master III June 28, 2007 23,432 234.32 - -------------------------------------------------------------------------------- Icahn Master III June 29, 2007 23,432 234.32 - -------------------------------------------------------------------------------- Icahn Master III July 2, 2007 9,406 94.06 - -------------------------------------------------------------------------------- Icahn Master III July 9, 2007 6,086 60.86 - -------------------------------------------------------------------------------- Icahn Master III July 10, 2007 2,604 26.04 - -------------------------------------------------------------------------------- Icahn Master III July 16, 2007 11,619 116.19 - -------------------------------------------------------------------------------- Icahn Master III July 17, 2007 20,217 202.17 - --------------------------------------------------------------------------------

Put options purchased by the Icahn Parties, which were written by Merrill Lynch International and had a $35.50 strike price, expiration date of November 26, 2008, and provided for cash settlement only and for exercise only at expiration are further described in the chart set forth below. All of the put options described below terminated on August 24, 2007. NAME DATE NUMBER OF OPTION SHARES SUBJECT PREMIUM TO OPTION ($) - -------------------------------------------------------------------------------- HIGH RIVER - -------------------------------------------------------------------------------- High River July 10, 2007 102,929 1,029.29 - -------------------------------------------------------------------------------- High River July 11, 2007 30,536 305.36 - -------------------------------------------------------------------------------- High River July 12, 2007 57,192 571.92 - -------------------------------------------------------------------------------- High River July 18, 2007 200,000 2,000.00 - -------------------------------------------------------------------------------- High River July 19, 2007 159,233 1,592.33 - -------------------------------------------------------------------------------- High River July 20, 2007 71,580 715.80 - -------------------------------------------------------------------------------- High River July 23, 2007 120,000 1,200.00 - -------------------------------------------------------------------------------- High River July 31, 2007 94,969 949.69 - -------------------------------------------------------------------------------- High River August 1, 2007 105,031 1,050.31 - -------------------------------------------------------------------------------- ICAHN PARTNERS - -------------------------------------------------------------------------------- Icahn Partners July 10, 2007 132,074 1,320.74 - -------------------------------------------------------------------------------- Icahn Partners July 11, 2007 39,181 391.81 - -------------------------------------------------------------------------------- Icahn Partners July 12, 2007 73,385 733.85 - -------------------------------------------------------------------------------- Icahn Partners July 18, 2007 256,627 2,566.27 - -------------------------------------------------------------------------------- Icahn Partners July 19, 2007 204,318 2,043.18 - -------------------------------------------------------------------------------- Icahn Partners July 20, 2007 91,847 918.47 - -------------------------------------------------------------------------------- Icahn Partners July 23, 2007 153,977 1,539.77 - -------------------------------------------------------------------------------- Icahn Partners July 31, 2007 121,987 1,219.87 - -------------------------------------------------------------------------------- Icahn Partners August 1, 2007 141,380 1,413.80 - -------------------------------------------------------------------------------- ICAHN MASTER - -------------------------------------------------------------------------------- Icahn Master July 10, 2007 192,685 1,926.85 - -------------------------------------------------------------------------------- Icahn Master July 11, 2007 57,163 571.63 - -------------------------------------------------------------------------------- Icahn Master July 12, 2007 107,064 1,070.64 - -------------------------------------------------------------------------------- Icahn Master July 18, 2007 374,402 3,744.02 - -------------------------------------------------------------------------------- Icahn Master July 19, 2007 298,086 2,980.86 - -------------------------------------------------------------------------------- Icahn Master July 20, 2007 133,999 1,339.99 - -------------------------------------------------------------------------------- Icahn Master July 23, 2007 224,640 2,246.40 - -------------------------------------------------------------------------------- Icahn Master July 31, 2007 177,800 1,778.00 - -------------------------------------------------------------------------------- Icahn Master August 1, 2007 182,136 1,821.36 - -------------------------------------------------------------------------------- ICAHN MASTER II - -------------------------------------------------------------------------------- Icahn Master II July 10, 2007 63,042 630.42 - -------------------------------------------------------------------------------- Icahn Master II July 11, 2007 18,702 187.02 - -------------------------------------------------------------------------------- Icahn Master II July 12, 2007 35,029 350.29 - -------------------------------------------------------------------------------- Icahn Master II July 18, 2007 122,495 1,224.95 - -------------------------------------------------------------------------------- Icahn Master II July 19, 2007 97,526 975.26 - -------------------------------------------------------------------------------- Icahn Master II July 20, 2007 43,842 438.42 - -------------------------------------------------------------------------------- Icahn Master II July 23, 2007 73,498 734.98 - -------------------------------------------------------------------------------- Icahn Master II July 31, 2007 58,078 580.78 - -------------------------------------------------------------------------------- Icahn Master II August 1, 2007 71,170 711.70 - -------------------------------------------------------------------------------- ICAHN MASTER III - -------------------------------------------------------------------------------- Icahn Master III July 10, 2007 23,917 239.17 - -------------------------------------------------------------------------------- Icahn Master III July 11, 2007 7,097 70.97 - -------------------------------------------------------------------------------- Icahn Master III July 12, 2007 13,290 132.90 - -------------------------------------------------------------------------------- Icahn Master III July 18, 2007 46,476 464.76 - -------------------------------------------------------------------------------- Icahn Master III July 19, 2007 37,004 370.04 - -------------------------------------------------------------------------------- Icahn Master III July 20, 2007 16,632 166.32 - -------------------------------------------------------------------------------- Icahn Master III July 23, 2007 27,885 278.85 - -------------------------------------------------------------------------------- Icahn Master III July 31, 2007 22,013 220.13 - -------------------------------------------------------------------------------- Icahn Master III August 1, 2007 25,436 254.36 - --------------------------------------------------------------------------------

ANNEX B FORM OF NOMINEE AGREEMENT ICAHN PARTNERS LP ICAHN PARTNERS MASTER FUND LP ICAHN PARTNERS MASTER FUND II LP ICAHN PARTNERS MASTER FUND III LP HIGH RIVER LIMITED PARTNERSHIP January 24, 2008 [NAME OF NOMINEE] Dear ___________: This will confirm our understanding as follows: You agree that you are willing, should we so elect, to become a member of a slate of nominees (the "Slate") to stand for election as directors of Biogen Idec Inc. ("Biogen") in connection with a proxy contest with management of Biogen in respect of the election of directors of Biogen at the 2008 Annual Meeting of Stockholders of Biogen (the "Annual Meeting"), expected to be held in the Spring of 2008, or a special meeting of stockholders of Biogen called for a similar purpose (the "Proxy Contest"). Icahn Partners LP, Icahn Partners Master Fund LP, Icahn Partners Master Fund II LP, Icahn Partners Master Fund III LP and High River Limited Partnership (collectively, "Icahn"), agree to pay the costs of the Proxy Contest. In addition, upon our filing of a preliminary proxy statement with the SEC, which indicates that Icahn intends to nominate you for election at the Annual Meeting, you will be paid $25,000 by Icahn. You understand that it may be difficult, if not impossible, to replace nominees who, such as yourself, have agreed to serve on the Slate and later change their minds and determine not to seek election. Accordingly, the Slate is relying upon your agreement to seek election. In that connection, you are being supplied with a questionnaire in which you will provide Icahn with information necessary for Icahn to make appropriate disclosure both to Biogen and for use in creating the proxy material to be sent to stockholders of Biogen and to be filed with the Securities and Exchange Commission. You have agreed that (i) you will immediately complete and sign the questionnaire and return it to Andrew Langham, Counsel, Icahn Enterprises L.P., 767 Fifth Avenue, Suite 4700, New York, NY 10153, Tel: (212) 702-4382, Fax: (212) 688-1158, Email: alangham@sfire.com, and (ii) your responses to the questions contained therein will be true and correct in all respects. In addition, you have agreed that, concurrently with your execution of this letter, you will execute the attached instrument directed to Biogen informing Biogen that you consent to being nominated by Icahn for election as a director of Biogen and, if elected, consent to serving as a director of Biogen. Upon being notified that we have chosen you, we may forward that consent and your completed questionnaire (or summaries thereof) to Biogen. Icahn hereby agrees that, so long as you actually serve on the Slate, Icahn will defend, indemnify and hold you harmless from and against any and all losses, damages, penalties, judgments, awards, liabilities, costs, expenses and disbursements (including, without limitation, reasonable attorneys' fees, costs, expenses and disbursements) incurred by you in the event that (i) you become a party, or are threatened to be made a party, to any civil, criminal, administrative or arbitrative action, suit or proceeding, and any appeal thereof relating solely to your role as a nominee for director of Biogen on the Slate (a "Proceeding") or (ii) you are called to testify or give a deposition in any Proceeding (whether or not you are a party or are threatened to be made a party to such Proceeding), including, in each case, the advancement to you of all reasonable attorneys' costs and expenses incurred by you in connection with any Proceeding. Your right of indemnification hereunder shall continue (i) in the event that Icahn determines to withdraw the Slate or remove you from the Slate and (ii) after the election has taken place but only for events which occur prior to such election and subsequent to the date hereof. Anything to the contrary herein notwithstanding, Icahn is not indemnifying you for any action taken by you or on your behalf which occurs prior to the date hereof or subsequent to the Annual Meeting or such earlier time as you are no longer a nominee of the Slate for election to Biogen's Board of Directors or for any actions taken by you as a director of Biogen, if you are elected. Nothing herein shall be construed to provide you an indemnity: (i) in the event you are found to have engaged in a violation of any provision of state or federal law in connection with the Proxy Contest unless you demonstrate that your action was taken in good faith and in a manner you reasonably believed to be in or not opposed to the best interests of electing the Slate; or (ii) if you acted in a manner which constitutes gross negligence or willful misconduct. In the event that you shall make any claim for indemnification hereunder, you shall promptly notify Icahn in the event of any third-party claims actually made against you or known by you to be threatened. In addition, with respect to any such claim, Icahn shall be entitled to control your defense with counsel chosen by Icahn. Icahn shall not be responsible for any settlement of any claim against you covered by this indemnity without its prior written consent. However, Icahn may not enter into any settlement of any such claim without your consent unless such settlement includes a release of you from any and all liability in respect of such claim. Each of us recognizes that should you be elected to the Board of Directors of Biogen all of your activities and decisions as a director will be governed by applicable law and subject to your fiduciary duty to the stockholders of Biogen and, as a result, that there is, and can be, no agreement between you and Icahn which governs the decisions which you will make as a director of Biogen. Should the foregoing agree with your understanding, please so indicate in the space provided below, whereupon this letter will become a binding agreement between us. Very truly yours, ICAHN PARTNERS LP By: __________________________ Name: Keith Meister Title: Authorized Signatory ICAHN PARTNERS MASTER FUND LP By: __________________________ Name: Keith Meister Title: Authorized Signatory ICAHN PARTNERS MASTER FUND II LP By: __________________________ Name: Keith Meister Title: Authorized Signatory ICAHN PARTNERS MASTER FUND III LP By: __________________________ Name: Keith Meister Title: Authorized Signatory HIGH RIVER LIMITED PARTNERSHIP By: Hopper Investments LLC, its general partner By: Barberry Corp., its sole member By: __________________________ Name: Keith Cozza Title: Treasurer and Secretary Agreed to and Accepted as of the date first above written: - -------------------------------- Name:

IMPORTANT 1. If your shares are held in your own name, please mark, date and mail the enclosed GOLD proxy card to our Proxy Solicitor, Georgeson Inc., in the postage-paid envelope provided. 2. If your shares are held in the name of a brokerage firm, bank nominee or other institution, only it can vote such shares and only upon receipt of your specific instructions. Accordingly, you should contact the person responsible for your account and give instructions for a GOLD proxy card to be signed representing your shares. 3. If you have already submitted a white proxy card to Biogen for the Annual Meeting, you may change your vote to a vote FOR the election of the Nominee by marking, signing, dating and returning the enclosed GOLD proxy card for the Annual Meeting, which must be dated after any proxy you may have submitted to Biogen. You may also submit your later-dated proxy by using the enclosed GOLD proxy card to vote by telephone or by Internet. ONLY YOUR LATEST DATED PROXY FOR THE ANNUAL MEETING WILL COUNT AT THE ANNUAL MEETING. If you have any questions or require any assistance in executing your proxy, please call: Georgeson Inc. Stockholders call toll-free: (800) 377-9583 Banks and Brokers call collect: (212) 440-9800

YOUR VOTE IS IMPORTANT PLEASE COMPLETE, DATE, SIGN AND MAIL YOUR PROXY CARD IN THE ENVELOPE PROVIDED AS SOON AS POSSIBLE. TO VOTE BY MAIL, PLEASE DETACH PROXY CARD HERE BIOGEN IDEC, INC. 2008 ANNUAL MEETING OF STOCKHOLDERS THIS PROXY IS SOLICITED BY CARL C. ICAHN, ALEXANDER J. DENNER, ANNE B. YOUNG, RICHARD C. MULLIGAN, VINCENT J. INTRIERI, KEITH A. MEISTER, DAVID SCHECHTER, ICAHN PARTNERS LP, ICAHN PARTNERS MASTER FUND LP, ICAHN PARTNERS MASTER FUND II LP, ICAHN PARTNERS MASTER FUND III LP, HIGH RIVER LIMITED PARTNERSHIP, BARBERRY CORP., HOPPER INVESTMENTS LLC, ICAHN OFFSHORE LP, ICAHN ONSHORE LP, ICAHN CAPITAL LP, IPH GP LLC, ICAHN ENTERPRISES HOLDINGS L.P., ICAHN ENTERPRISES G.P. INC., AND BECKTON CORP. The undersigned hereby appoints and constitutes each of Carl C. Icahn, Dr. Alexander J. Denner and Keith A. Meister, (acting alone or together) as proxies, with full power of substitution in each, to represent the undersigned at the Annual Meeting of Stockholders of Biogen Idec, Inc. ("Biogen") to be held on June 19, 2008 at 9:00 a.m. local time, at the America Academy of Arts & Sciences, 136 Irving Street, Cambridge, MA 02138, and at any adjournment or postponement thereof, hereby revoking any proxies previously given, to vote all shares of Common Stock of Biogen held or owned by the undersigned as directed below, and in their discretion upon such other matters as may come before the meeting. IF NO DIRECTION IS MADE WITH RESPECT TO A PROPOSAL, THIS PROXY WILL BE VOTED AS FOLLOWS WITH RESPECT TO ANY SUCH PROPOSAL: (I) FOR DR. ALEXANDER J. DENNER FOR DIRECTOR; (II) FOR DR. ANNE B. YOUNG FOR DIRECTOR; (III) FOR PROFESSOR RICHARD C. MULLIGAN FOR DIRECTOR; (IV) FOR THE PERSON WHO HAS BEEN NOMINATED BY BIOGEN TO SERVE AS DIRECTOR, OTHER THAN MR. CECIL B. PICKETT, MS. LYNN SCHENK AND MR. STELIOS PAPADOPOULOS; (V) FOR THE BYLAW AMENDMENTS; (VI) FOR THE RATIFICATION OF SELECTION OF THE INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM; (VII) AGAINST BIOGEN'S 2008 OMNIBUS EQUITY PLAN; (VIII) AGAINST BIOGEN'S 2008 PERFORMANCE-BASED MANAGEMENT INCENTIVE PLAN; AND (IX) IN THE PROXY HOLDERS' DISCRETION AS TO OTHER MATTERS THAT MAY PROPERLY COME BEFORE THE ANNUAL MEETING. If any nominee for director is unable or declines to serve as director, this proxy will be voted for any nominee that any of Icahn Partners LP, Icahn Partners Master Fund LP, Icahn Partners Master Fund II LP, Icahn Partners Master Fund III LP or High River Limited Partnership (collectively, the "Icahn Parties") designates. YOUR VOTE IS VERY IMPORTANT--PLEASE VOTE YOUR PROXY TODAY. (CONTINUED AND TO BE SIGNED AND DATED ON THE REVERSE SIDE.)

THERE ARE THREE WAYS TO AUTHORIZE THE PROXIES TO CAST YOUR VOTES YOUR TELEPHONE OR INTERNET VOTE AUTHORIZES THE NAMED PROXIES TO VOTE YOUR SHARES IN THE SAME MANNER AS IF YOU HAD RETURNED YOUR PROXY CARD. WE ENCOURAGE YOU TO USE THESE COST EFFECTIVE AND CONVENIENT WAYS OF VOTING, 24 HOURS A DAY, 7 DAYS A WEEK. TELEPHONE VOTING INTERNET VOTING VOTING BY MAIL This method of voting is available for Visit the Internet voting Web site at Simply sign and date your proxy card and residents of the U.S. and Canada. On a http://proxy.georgeson.com. Have this return it in the postage-paid envelope to touch tone telephone, call TOLL FREE 1- proxy card ready and follow the instruc- Georgeson Inc., Wall Street Station, P.O. 866-219-9799, 24 hours a day, 7 days a tions on your screen. You will incur Box 1100, New York, NY 10269-0646. If you week. Have this proxy card ready, then only your usual Internet charges. are voting by telephone or the Internet, follow the prerecorded instructions. Available 24 hours a day, 7 days a please do not mail your proxy card. You vote will be confirmed and cast as week until 5:00 p.m. Eastern Daylight you have directed. Available 24 hours Time on June 18, 2008. a day, 7 days a week until 5:00 p.m. Eastern Daylight Time on June 18, 2008. DETACH BELOW AND RETURN USING THE ENVELOPE PROVIDED ONLY IF YOU ARE VOTING BY MAIL PLEASE MARK [X] VOTES AS IN THIS EXAMPLE. THE ICAHN PARTIES RECOMMEND A VOTE "FOR" THE ELECTION OF ITS NOMINEES AND "FOR" PROPOSALS 2 AND 3, AND "AGAINST" PROPOSALS 4 AND 5. PROPOSAL 1: To elect: WITHHOLD AUTHORITY FOR ALL (01) Dr. Alexander J. Denner, as director FOR ALL TO VOTE FOR Nominees Nominees All Nominees EXCEPT (02) Dr. Anne B. Young, as director and [ ] [ ] [ ] (03) Professor Richard C. Mulligan, as director The Icahn Parties intend to use this proxy to vote (i) FOR Dr. Alexander J. Denner, (ii) FOR Dr. Anne B. Young, (iii) FOR Professor Richard C. Mulligan, (iv) FOR the person who has been nominated by Biogen to serve as director, other than Mr. Cecil B. Pickett, Ms. Lynn Schenk, and Mr. Stelios Papadopoulos, (v) FOR the Bylaw Amendments, (vi) FOR the ratification of selection of the Independent Registered Public Accounting Firm, (vii) AGAINST Biogen's 2008 Omnibus Equity Plan, (viii) AGAINST Biogen's 2008 Performance-Based Management Incentive Plan, and (ix) in the proxy holder's discretion as to other matters that may properly come before the annual meeting. The Icahn Parties are NOT seeking authority to vote for and WILL NOT exercise any authority to vote for Mr. Cecil B. Pickett, Ms. Lynn Schenk, and Mr. Stelios Papadopoulos. There is no assurance that any of the Biogen nominees will serve as directors if any or all of the Icahn Parties' nominees are elected to the Board. You should refer to the proxy statement and form of proxy distributed by Biogen for the names, background, qualifications and other information concerning the Biogen nominees. NOTE: IF YOU DO NOT WISH FOR YOUR SHARES TO BE VOTED "FOR" A PARTICULAR ICAHN PARTIES' NOMINEE, MARK THE "FOR ALL NOMINEES EXCEPT" BOX AND WRITE THE NAME(S) OF THE NOMINEE(S) YOU DO NOT SUPPORT ON THE LINE BELOW. YOU MAY ALSO WITHHOLD AUTHORITY TO VOTE FOR THE PERSON WHO HAS BEEN NOMINATED BY BIOGEN TO SERVE AS DIRECTOR OTHER THAN MR. CECIL B. PICKETT, MS. LYNN SCHENK, AND MR. STELIOS PAPADOPOULOS BY WRITING THE NAME OF THE NOMINEE BELOW: _________________________________________________________ - ------------------------------------------------------------------------------------------------------------------------------------ PROPOSAL 2: Approval of the Bylaw Amendments FOR AGAINST ABSTAIN [ ] [ ] [ ] PROPOSAL 3: Ratification of Independent Registered Public Accounting Firm [ ] [ ] [ ] PROPOSAL 4: Approval of 2008 Omnibus Equity Plan [ ] [ ] [ ] PROPOSAL 5: Approval of 2008 Performance-Based Management Incentive Plan [ ] [ ] [ ] Dated: _______________, 2008 ____________________________ Signature(s) ____________________________ Signature (if held jointly) ____________________________ Title(s), if any Please sign exactly as your name(s) appear(s) hereon. If shares are issued in the name of two or more persons, all such persons should sign the proxy. A proxy executed by a corporation or other company should be signed in its name by its authorized officers. Executors, administrators, trustees and partners should indicate their positions when signing.