United States securities and exchange commission logo June 22, 2021 Michael McDonnell Executive Vice President and Chief Financial Officer BIOGEN INC. 225 Binney Street Cambridge, MA 02142 Re: BIOGEN INC. Form 10-K for Fiscal Year Ended December 31, 2020 Filed February 3, 2021 File No. 000-19311 Dear Mr. McDonnell: We have completed our review of your filing. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Sincerely, Division of Corporation Finance Office of Life Sciences